130 Participants Needed

Early Chest Tube Removal for Lung Surgery

(PROTECTR Trial)

DL
Overseen ByDeb Lewis
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Lawson Health Research Institute
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 1 JurisdictionThis treatment is already approved in other countries

Trial Summary

Do I need to stop taking my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What data supports the effectiveness of the treatment Early Chest Tube Removal for Lung Surgery?

Research suggests that early removal of chest tubes after lung surgery can reduce postoperative pain and speed up recovery, as seen in studies involving early removal of pigtail catheters and chest tubes after lung surgeries.12345

Is early chest tube removal generally safe for humans?

Research shows that early chest tube removal after lung surgery is generally safe and can help reduce pain and speed up recovery. However, in some cases, like after a complex lung surgery, there might be risks such as air leaks or fluid buildup, which could delay removal.34567

How is the treatment of early chest tube removal for lung surgery different from other treatments?

Early chest tube removal after lung surgery is unique because it aims to reduce postoperative pain and speed up recovery by removing the chest tube sooner than traditional methods, which typically involve keeping the tube in place for a longer period to ensure proper drainage.12348

What is the purpose of this trial?

This study is a single centre, prospective clinical trial evaluating the safety and feasibility of implementing a same day chest tube removal protocol in patients undergoing Video Assisted Thoracic Surgery (VATS) anatomical pulmonary surgery.

Research Team

RN

Rahul Nayak, MD MSc

Principal Investigator

Western University

Eligibility Criteria

This trial is for patients who have undergone a minimally invasive lung surgery called VATS. It's testing if it's safe and possible to remove the chest tube on the same day of surgery, which could enhance recovery.

Inclusion Criteria

I am scheduled for a specific lung surgery.

Exclusion Criteria

I have had a procedure to fuse the layers of my lung lining.
My surgery was changed to an open chest operation while in progress.
I cannot complete daily tasks due to a cognitive disorder.
See 1 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants undergo Video Assisted Thoracic Surgery (VATS) with early chest tube removal at 3 hours post-operation

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment, including assessment of complications and quality of life

30 days
Multiple visits (in-person and virtual)

Treatment Details

Interventions

  • Early Chest Tube Removal
Trial Overview The study is examining the outcomes when chest tubes are removed early after Video Assisted Thoracic Surgery (VATS). The goal is to see if this can be part of an improved recovery protocol.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Early Chest Tube RemovalExperimental Treatment1 Intervention
early chest tube removal at 3 hours
Group II: Standard of CareActive Control1 Intervention
Routine post operative chest tube care

Find a Clinic Near You

Who Is Running the Clinical Trial?

Lawson Health Research Institute

Lead Sponsor

Trials
684
Recruited
432,000+

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Lead Sponsor

Trials
678
Recruited
421,000+

London Health Sciences Centre OR Lawson Research Institute of St. Joseph's

Lead Sponsor

Trials
668
Recruited
424,000+

London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's

Lead Sponsor

Trials
686
Recruited
427,000+

Findings from Research

In a study of 1232 patients who underwent cardiac surgery, early removal of chest tubes (around midnight) was linked to a higher risk of developing postoperative pleural and/or pericardial effusions requiring invasive treatment, with a relative risk of 1.70.
Patients who had their chest tubes removed early had a 20% incidence of complications compared to 13% in those who had tubes removed the following morning, suggesting that delaying removal may enhance patient safety.
Early chest tube removal following cardiac surgery is associated with pleural and/or pericardial effusions requiring invasive treatment.Andreasen, JJ., Sørensen, GV., Abrahamsen, ER., et al.[2015]
In a study of 162 patients undergoing thoracoscopic lung resection, a no-drain policy was found to be safe, with no postoperative mortality or need for redrainage in patients who had their chest tubes removed immediately after surgery.
Patients who did not have chest tubes placed experienced shorter hospital stays and less postoperative pain compared to those who did, suggesting that omitting chest tube drainage can enhance recovery after lung surgery.
The Validation of a No-Drain Policy After Thoracoscopic Major Lung Resection.Murakami, J., Ueda, K., Tanaka, T., et al.[2022]
In a study of 126 patients with stage I lung cancer undergoing uniportal video-assisted thoracic surgery, early removal of the pigtail catheter within 24 hours post-surgery was found to be safe and feasible, with no significant complications requiring tube reinsertion for pneumothorax during the 30-day follow-up.
Patients who had their chest tubes removed within 24 hours experienced significantly less pain on the third postoperative day compared to those who had their tubes removed after 24 hours, suggesting that early removal may enhance recovery comfort.
The short-term outcomes for the early removal of pigtail catheter drainage within 24 hours of uniportal video-assisted anatomic surgery in patients with lung cancer.Zheng, S., Shi, Q., Ma, Q., et al.[2022]

References

Early chest tube removal following cardiac surgery is associated with pleural and/or pericardial effusions requiring invasive treatment. [2015]
The Validation of a No-Drain Policy After Thoracoscopic Major Lung Resection. [2022]
The short-term outcomes for the early removal of pigtail catheter drainage within 24 hours of uniportal video-assisted anatomic surgery in patients with lung cancer. [2022]
[Early removal of the chest tube after lobectomies: a prospective randomized control study]. [2013]
A prospective study of the association between drainage volume within 24 hours after thoracoscopic lobectomy and postoperative morbidity. [2022]
Early postoperative day 0 chest tube removal using a digital drainage device protocol after thoracoscopic major pulmonary resection. [2021]
Safety of early discharge with a chest tube after pulmonary segmentectomy. [2021]
Early chest tube removal after thoracoscopic lobectomy with the aid of an additional thin tube: a prospective multi-institutional study. [2022]
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