Two Photon Microscopy for Skin Cancer
Trial Summary
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Two-photon microscopy imaging for skin cancer?
Research shows that two-photon microscopy can help visualize skin cancer by providing detailed images of skin tissue without needing to cut it. This method has been used successfully in studies to diagnose skin conditions quickly and non-invasively, which could lead to faster treatment decisions.12345
Is two-photon microscopy safe for use in humans?
How is two-photon microscopy imaging different from other skin cancer treatments?
Two-photon microscopy imaging is unique because it allows for high-resolution, real-time imaging of skin layers without needing to cut the skin, using ultrashort laser pulses to visualize cells and structures up to 1 mm deep. This non-invasive method provides detailed insights into skin cancer and other conditions, unlike traditional methods that may require tissue samples.12357
What is the purpose of this trial?
This trial aims to see if a special imaging technique called TPFM can help doctors find any remaining cancer cells during skin cancer surgery. It focuses on patients with basal cell carcinoma and compares TPFM results with other methods to ensure accuracy.
Research Team
Michael G Giacomelli, Ph.D
Principal Investigator
University of Rochester
Eligibility Criteria
This trial is for individuals who can read and understand a consent form and are currently undergoing Mohs surgery for basal cell carcinoma (BCC) at the location where the study is being conducted.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo Mohs surgery with TPFM imaging of surgical margins followed by standard of care frozen section analysis
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Two photon microscopy imaging
Two photon microscopy imaging is already approved in United States, European Union for the following indications:
- Diagnostic tool for non-melanoma skin cancers, including basal cell carcinoma and squamous cell carcinoma
- Research and diagnostic tool for skin cancers, including basal cell carcinoma
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Rochester
Lead Sponsor
Rochester Dermatologic Surgery
Collaborator