Pomegranate Supplement for Burnout
Trial Summary
Will I have to stop taking my current medications?
Yes, you will need to stop taking any chronic medications and supplements, including over-the-counter multivitamins, to participate in this trial.
Is pomegranate extract safe for human consumption?
How does the pomegranate extract treatment for burnout differ from other treatments?
Pomegranate extract is unique because it is rich in antioxidants, which help reduce oxidative stress, a factor that can contribute to burnout. Unlike other treatments, it is derived from a natural source and has shown potential benefits in improving cardiovascular health and reducing inflammation, which may indirectly support mental well-being.34678
What is the purpose of this trial?
This trial will test if taking pomegranate supplements can help reduce stress and improve well-being in medical students and residents who experience high levels of mental distress and burnout.
Research Team
Joshua Mann, MD, MPH
Principal Investigator
University of Mississippi Medical Center
Eligibility Criteria
This trial is for first or second year medical students and residents at the University of Mississippi Medical Center. It's not suitable for those who are pregnant, planning to become pregnant, breastfeeding, taking chronic medications (other than contraception), using supplements, allergic to pomegranate or gelatin, or have severe depression or anxiety based on DASS-21 scores.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Pilot Treatment
10 participants receive the pomegranate supplement for 28 days
Randomized Treatment
40 participants are randomized to receive either the pomegranate supplement or a placebo for 28 days
Follow-up
Participants are monitored for changes in mental health symptoms, burnout, fatigue, and various biomarkers
Treatment Details
Interventions
- Placebo
- Pomella pomegranate extract
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Mississippi Medical Center
Lead Sponsor
University of Rhode Island
Collaborator