Culturally Tailored HPV Education for Vaccine Uptake

Overseen By Jacquelin Cordero, LMSW

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: University of Texas, El Paso

Disqualifiers: Age, Location, Language, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 2

100 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how different types of educational videos about the human papillomavirus (HPV) can influence vaccination rates. The researchers aim to determine if videos tailored to the cultural backgrounds of viewers in the El Paso, Texas region lead to higher vaccination rates than standard educational materials. Suitable participants are adults aged 18 to 45 living or working in El Paso County who haven't completed the HPV vaccine series. As an unphased trial, this study offers participants the chance to contribute to important research that could enhance public health education strategies.

Do I have to stop taking my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It seems to focus on educational interventions, so it's unlikely that you'll need to change your medication routine.

What prior data suggests that these multimedia interventions are safe?

In a previous study, researchers examined a multimedia program designed to teach people about the HPV vaccine in a culturally relevant way. This program used audio and video to make the information engaging and relatable. The study found that participants appreciated this multimedia approach and felt they learned more about HPV and the vaccine.

Regarding safety, watching educational videos poses no known risks. Studies have reported no negative effects, indicating that it is generally safe. These programs aim to improve understanding and encourage positive views about vaccination, allowing participants to feel confident in the safety of the experience. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores a new way to increase HPV vaccine uptake using culturally tailored multimedia education. Unlike standard HPV educational materials that are more generic, this intervention is specifically designed to resonate with diverse cultural backgrounds, which can potentially improve understanding and acceptance of the vaccine. By tailoring the content to specific cultural needs and values, the intervention could address barriers to vaccination and encourage more people to get vaccinated. This approach could lead to higher vaccination rates and ultimately better protection against HPV-related diseases.

What evidence suggests that this trial's interventions could be effective for increasing HPV vaccine uptake?

This trial will compare a Culturally Tailored Multimedia Psychoeducational HPV Intervention with a General HPV Multimedia Psychoeducational Control Group. Research has shown that culturally tailored multimedia can boost HPV vaccination rates. When educational materials resonate with a specific group's culture and experiences, vaccination likelihood increases. For instance, a study with African American girls used this approach and observed significant improvements in overcoming vaccination barriers. Personalized stories and content can influence how people understand and respond to health information. By adjusting messages to fit cultural backgrounds, these interventions aim to increase vaccine uptake. ^{1 2 3 6 7}

Who Is on the Research Team?

Eva M Moya, PhD, LMSW

Principal Investigator

The University of Texas at El Paso, Border Biomedical Research Center

Are You a Good Fit for This Trial?

This trial is for adults aged 18-45 who live or work in El Paso County, Texas and haven't finished their HPV vaccine series. It's not for those under 18 or over 45, non-residents of El Paso, or anyone who took part in earlier phases of this research.

Inclusion Criteria

I have not completed the HPV vaccine series.

You are an adult resident or employee of El Paso County, Texas.

Exclusion Criteria

Adults who participated in Phases I or II of the larger research project [cross-sectional phases]

Adults that do not reside, plan to live or work in El Paso County, Texas, within the next 12 months after the start of the intervention

I am older than 45 years.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive either a tailored HPV psychoeducational multimedia intervention or standard multimedia materials on HPV and HPV vaccine

0 months

1 visit (in-person or virtual)

Follow-up

Participants are monitored for changes in HPV knowledge, vaccination decision stage, and vaccine attitudes

1 month

1 visit (virtual)

What Are the Treatments Tested in This Trial?

Interventions

• Culturally Tailored Multimedia Psychoeducational HPV Intervention
• General HPV Multimedia Psychoeducational Control Group

Trial Overview The study compares two educational videos about HPV vaccination: one tailored to the local culture and another general information video. The goal is to see if the culturally tailored version leads to higher vaccination rates.

How Is the Trial Designed?

Group I: Treatment Experimental Treatment 1 Intervention

A tailored HPV psychoeducational multimedia intervention

Group II: Active Control Active Control 1 Intervention

General/standard multimedia materials on HPV and HPV vaccine

Who Is Running the Clinical Trial?

University of Texas, El Paso

Lead Sponsor

Trials

17

Recruited

3,000+

National Institute on Minority Health and Health Disparities (NIMHD)

Collaborator

Trials

473

Recruited

1,374,000+

Citations

1. trialx.com trialx.com/clinical-trials/listings/301813/culturally-tailored-hpv-psychoeducational-multimedia-intervention/

Culturally Tailored HPV Psychoeducational Multimedia ... Our hypothesis is that adults who view culturally tailored multimedia stories encouraging HPV vaccination will report higher vaccine uptake ...

2. careacross.com careacross.com/clinical-trials/trial/NCT06098690

Culturally Tailored HPV Psychoeducational Multimedia ... Our hypothesis is that adults who view culturally tailored multimedia stories encouraging HPV vaccination will report higher vaccine uptake rates. Detailed ...

3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC12006767/

Web-Based Human Papillomavirus Education and ... This study aims to compare HPV educational and professional skills intervention effectiveness on improving provider recommendations and patient communication ...

4. sciencedirect.com sciencedirect.com/science/article/pii/S0264410X25006565

Review Effective strategies in human papillomavirus (HPV) ... Overcoming barriers to HPV vaccination: a randomized clinical trial of a culturally-tailored, media intervention among African American girls.

5. nature.com nature.com/articles/s41746-023-00912-w

Systematic review and meta-analysis comparing ... Overcoming barriers to HPV vaccination: A randomized clinical trial of a culturally-tailored, media intervention among African American girls.

6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC5054780/

Overcoming barriers to HPV vaccination: A randomized ... This study examines an innovative culturally tailored, computer-delivered media-based strategy to promote HPV vaccine uptake.

7. formative.jmir.org formative.jmir.org/2024/1/e59087

eHealth Communication Intervention to Promote Human ... This study aims to investigate the feasibility and usability of an eHealth communication intervention for HPV vaccination in middle-school girls.