Aerobic Exercise Training for Breast Cancer

University of Nebraska Medical Center, Omaha, NE
Targeting 2 different conditionsAerobic Exercise Training +1 moreN/AWaitlist AvailableLed by Diane K Ehlers, PhDResearch Sponsored by University of Nebraska

Study Summary

This trial will test if exercise can improve cognitive function in post-menopause breast cancer survivors.

Eligible Conditions
  • Breast Cancer

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below
You have self-reported exercising for twenty minutes or more on two days or fewer per week in the last six months.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline (month 0), post-intervention (month 6), follow up (month 12)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (month 0), post-intervention (month 6), follow up (month 12) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in brain volume
Change in cognitive flexibility
Change in executive function processing
+9 more
Secondary outcome measures
+1 more
Other outcome measures
Change in Cancer-related Fatigue
Change in Cardiorespiratory Fitness

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Aerobic Exercise TrainingExperimental Treatment1 Intervention
Breast cancer survivors randomized to the intervention group will participate in a moderate-intensity aerobic exercise program for 24 weeks.
Group II: Health Education (Control)Active Control1 Intervention
Individuals randomized to Health Education will receive individual education and counseling related to general cancer-related health and support across 24 weeks.
First Studied
Drug Approval Stage
How many patients have taken this drug
Aerobic Exercise Training
Completed Phase 4

Find a site

Who is running the clinical trial?

University of NebraskaLead Sponsor
514 Previous Clinical Trials
1,152,158 Total Patients Enrolled
14 Trials studying Breast Cancer
1,006,142 Patients Enrolled for Breast Cancer
Mayo ClinicLead Sponsor
3,048 Previous Clinical Trials
3,484,575 Total Patients Enrolled
80 Trials studying Breast Cancer
13,869 Patients Enrolled for Breast Cancer
Diane K Ehlers, PhDPrincipal Investigator
Mayo Clinic
3 Previous Clinical Trials
60 Total Patients Enrolled
1 Trials studying Breast Cancer
30 Patients Enrolled for Breast Cancer

Media Library

Aerobic Exercise Training Clinical Trial Eligibility Overview. Trial Name: NCT04816006 — N/A
Breast Cancer Research Study Groups: Health Education (Control), Aerobic Exercise Training
Breast Cancer Clinical Trial 2023: Aerobic Exercise Training Highlights & Side Effects. Trial Name: NCT04816006 — N/A
Aerobic Exercise Training 2023 Treatment Timeline for Medical Study. Trial Name: NCT04816006 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
How old are they?
18 - 65
< 18
What site did they apply to?
University of Nebraska Medical Center
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
~107 spots leftby Apr 2026