Brain Stimulation for ADHD
JC
PC
Overseen ByPatricia Cirillo, MD, PhD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Massachusetts General Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing mild electrical brain stimulation to see how it affects brain function and thinking skills in people who might benefit from improved cognitive abilities.
Who Is on the Research Team?
JC
Joan Camprodon, MD, PhD, MPH
Principal Investigator
Massachusetts General Hospital
Are You a Good Fit for This Trial?
This trial is for adults aged 18-55 with ADHD, diagnosed per DSM-5 criteria. Participants can be on non-stimulant meds if the dose has been stable for 4 weeks. Those on stimulants must stop them two days before each study visit under a doctor's guidance but may resume between visits.Inclusion Criteria
Patients: A diagnosis of ADD/ADHD or meeting the DSM-5 criteria
I am not taking stimulant medications or am stopping them under doctor's advice.
I have been on the same non-stimulant medication dose for at least 4 weeks.
Exclusion Criteria
I am currently taking medication for mental health.
Healthy Control: Active substance dependence (except for tobacco)
Healthy Control: Pregnant or nursing females
See 7 more
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
2-4 weeks
Treatment
Participants receive anodal tDCS to the left DLPFC to assess cognitive and neurophysiological dose-response relationships
2-6 weeks
4 visits (in-person)
Follow-up
Participants are monitored for safety and effectiveness after treatment
4 weeks
What Are the Treatments Tested in This Trial?
Interventions
- tDCS
Trial Overview The study tests how different doses of Transcranial Direct Current Stimulation (tDCS) to the left DLPFC affect cognitive and brain functions in people with ADHD. It looks at various current intensities, electric field strengths, and durations of stimulation.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Group I: Healthy ControlExperimental Treatment1 Intervention
Volunteers without Neuropsychiatric Disorders.
Group II: ADHDExperimental Treatment1 Intervention
Patients with ADHD.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Massachusetts General Hospital
Lead Sponsor
Trials
3,066
Recruited
13,430,000+
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