40 Participants Needed

Watermelon for Satiety

Mee Young Hong, PhD profile photo
Overseen ByMee Young Hong, PhD
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: San Diego State University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 1 JurisdictionThis treatment is already approved in other countries

Trial Summary

Do I need to stop taking my current medications for the trial?

The trial requires that you do not need any medication for metabolic disorders, so if you are on such medications, you may need to stop taking them to participate.

What data supports the effectiveness of the treatment Fresh Watermelon Consumption for satiety?

Research shows that eating fresh watermelon can make people feel fuller compared to eating low-fat cookies, and it can help reduce body weight, body mass index (BMI), and blood pressure in overweight and obese adults.12345

Is watermelon consumption generally safe for humans?

Research suggests that watermelon consumption is generally safe for humans and may even offer health benefits like reducing blood pressure and improving diet quality. However, it may increase fasting blood sugar, so individuals with diabetes should be cautious.35678

How does fresh watermelon consumption as a treatment for satiety differ from other treatments?

Fresh watermelon consumption is unique because it not only helps with feeling full (satiety) but also contributes to weight loss, lowers blood pressure, and improves overall diet quality by providing essential nutrients like fiber, magnesium, and vitamin A. Unlike other treatments, it is a natural, nutrient-dense food that can enhance antioxidant capacity and reduce oxidative stress.568910

What is the purpose of this trial?

The goal of the proposed study is to determine the effects of fresh watermelon fruit consumption on satiety, metabolic parameters and weight management.

Eligibility Criteria

This trial is for adults aged 18-55 with a BMI between 25 and 40, who are not pregnant, do not smoke, don't need dietary supplements or medication for metabolic disorders, and have no allergies to watermelon or gluten.

Inclusion Criteria

Your body mass index (BMI) is between 25 and 40.

Exclusion Criteria

Pregnant woman
You are a person who smokes cigarettes.
You are required to take dietary supplements as part of the study.
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Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants consume fresh watermelon or low-fat cookies to assess effects on satiety and cardiometabolic health

2 hours per session
6 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

  • Fresh Watermelon Consumption
Trial Overview The study is looking at how eating fresh watermelon affects feelings of fullness (satiety), body weight management, and heart health compared to consuming low-fat cookies.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: WatermelonExperimental Treatment1 Intervention
Group II: Low fat cookiesActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

San Diego State University

Lead Sponsor

Trials
182
Recruited
119,000+

Findings from Research

Tomato soup significantly reduced the intake of a second course meal more than melon or cheese on crackers, indicating it is more effective at promoting satiety.
The effectiveness of tomato soup in reducing food intake is likely due to its low energy density, rather than sensory-specific satiety, suggesting it could be beneficial in weight management strategies.
Foods with different satiating effects in humans.Rolls, BJ., Fedoroff, IC., Guthrie, JF., et al.[2019]
Randomized controlled trials indicate that increasing whole, fresh fruit consumption can help with weight maintenance or modest weight loss over periods of 3 to 24 weeks, suggesting it may be beneficial for those looking to manage their weight.
Observational studies show that higher habitual fruit intake is generally not linked to weight gain and may even provide modest protection against it, reinforcing the idea that whole, fresh fruit does not contribute to obesity.
Impact of Whole, Fresh Fruit Consumption on Energy Intake and Adiposity: A Systematic Review.Guyenet, SJ.[2020]
Watermelon supplementation significantly reduced systolic blood pressure, total cholesterol, and low-density lipoprotein levels in a meta-analysis of 9 randomized controlled trials involving various participants.
While watermelon showed promising antihypertensive effects, it also led to an increase in fasting blood sugar, and the results for other cardiovascular risk factors were inconclusive, highlighting the need for further research with larger sample sizes and longer follow-up periods.
Watermelon consumption decreases risk factors of cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials.Karimi, E., Abaj, F., Gholizadeh, M., et al.[2023]

References

Foods with different satiating effects in humans. [2019]
Impact of Whole, Fresh Fruit Consumption on Energy Intake and Adiposity: A Systematic Review. [2020]
Watermelon consumption decreases risk factors of cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials. [2023]
Impact of a 3-Month Anti-inflammatory Dietary Intervention Focusing on Watermelon on Body Habitus, Inflammation, and Metabolic Markers: A Pilot Study. [2020]
Effects of Fresh Watermelon Consumption on the Acute Satiety Response and Cardiometabolic Risk Factors in Overweight and Obese Adults. [2023]
Consumer acceptability of low-sugar watermelon sweetened with non-calorie sweetener by a Native American community. [2016]
Versatile Nutraceutical Potentials of Watermelon-A Modest Fruit Loaded with Pharmaceutically Valuable Phytochemicals. [2021]
Watermelon Intake Is Associated with Increased Nutrient Intake and Higher Diet Quality in Adults and Children, NHANES 2003-2018. [2022]
The acute effects of baobab fruit ( Adansonia digitata) on satiety in healthy adults. [2018]
The effect of fruit in different forms on energy intake and satiety at a meal. [2021]
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