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Telemedicine Interventions for Aphasia (PICTURE IT Trial)

N/A

Recruiting

Led By Argye E Hillis, MD

Research Sponsored by Johns Hopkins University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 1 week after treatment

Awards & highlights

PICTURE IT Trial Summary

This trial will compare two treatments to see which works better for post-stroke aphasia. Results will help improve language skills.

Who is the study for?

This trial is for adults over 18 who've had a stroke between 1 to 4 months ago, leading to aphasia with difficulty in naming objects. Participants must be able to give consent and understand therapy tasks. It's not for those with severe vision/hearing loss, non-English speakers, or individuals with other brain-affecting diseases or severe psychiatric conditions.Check my eligibility

What is being tested?

The PICTURE IT study tests two language therapies using telemedicine for post-stroke aphasia: one stimulates the right side of the brain (PICTURE IT) and another computer-based treatment improves naming (CoDeLT). The effectiveness of each will be compared in a randomized order with blinded assessors.See study design

What are the potential side effects?

Since this trial involves behavioral language treatments rather than drugs, traditional side effects are not expected. However, participants may experience fatigue or frustration during therapy sessions due to the challenges associated with learning and practicing new skills.

PICTURE IT Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 1 week after treatment

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 1 week after treatment

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1 week after treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in discourse content as assessed by z-score for the number of meaning-carrying units used in describing a picture

Secondary outcome measures

Change in accuracy of naming actions as assessed by the Hopkins Action Naming Assessment form

Change in accuracy of naming objects as assessed by the Boston Naming Test

Change in discourse informational efficiency as assessed by z-score for the number of syllables of meaning-carrying units used in describing a picture

+1 more

PICTURE IT Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: PICTURE IT Intervention-CoDeLT InterventionExperimental Treatment2 Interventions

Participants will receive PICTURE IT Intervention for 15 sessions followed by Computer Delivered Lexical Treatment (CoDeLT)Intervention for 15 sessions

Group II: CoDeLT Intervention-PICTURE IT InterventionActive Control2 Interventions

Participants will receive Computer Delivered Lexical Treatment (CoDeLT) Intervention for 15 sessions followed by PICTURE IT Intervention for 15 sessions

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor

2,266 Previous Clinical Trials

14,837,427 Total Patients Enrolled

13 Trials studying Aphasia

1,019 Patients Enrolled for Aphasia

Argye E Hillis, MDPrincipal InvestigatorJohns Hopkins University

Media Library

CoDeLT Clinical Trial Eligibility Overview. Trial Name: NCT05845047 — N/A

Aphasia Research Study Groups: CoDeLT Intervention-PICTURE IT Intervention, PICTURE IT Intervention-CoDeLT Intervention

Aphasia Clinical Trial 2023: CoDeLT Highlights & Side Effects. Trial Name: NCT05845047 — N/A

CoDeLT 2023 Treatment Timeline for Medical Study. Trial Name: NCT05845047 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research endeavor permit people aged below seventy-five to take part?

"This clinical trial only accepts applicants between the ages of 18 to 99. However, there are 43 studies for minors and 1100 studies specifically designed for older adults over 65 years old."

Answered by AI

Are there any available slots for participants in this research endeavor?

"Affirmative. Clinicaltrials.gov's data indicates that this research study, initially advertised on May 31st 2023, is currently open for enrolment. 70 test subjects are needed from one medical centre."

Answered by AI

What is the aggregate tally of participants in this clinical trial?

"Correct. The clinical trial's information hosted on the website indicates that recruitment is ongoing, with an original post date of May 31st 2023 and last update being June 28th 2023. 70 participants are required to be recruited from one research facility."

Answered by AI

What type of participant is best suited for this clinical assessment?

"This medical trial seeks to admit 70 individuals, aged 18 or over, who have been diagnosed with aphasia as the result of stroke. In order for an individual to be eligible for this study they must also meet the following criteria: Display at least 20% errors in either Boston Naming Test or Hopkins Action Naming Assessment; Provide informed consent (or designate someone else); Have suffered their stroke between 1 and 4 months prior; Evince comprehension of therapy tasks through 5 probes."

Answered by AI