CSF Drain Placement for Aortic Aneurysm
Trial Summary
What is the purpose of this trial?
This trial aims to see if using CSF drains before surgery can prevent spinal cord injury in patients having endovascular thoracoabdominal aneurysm repair. The study focuses on patients at risk of spinal cord injury due to reduced blood flow during the procedure. CSF drains help by lowering pressure around the spinal cord, improving blood flow and potentially preventing injury. CSF drainage has been used to protect the spinal cord during thoracic and thoracoabdominal aortic surgeries by reducing the risk of paraplegia.
Research Team
Adam Beck, MD
Principal Investigator
University of Alabama at Birmingham
Eligibility Criteria
This trial is for adults over 18 who are undergoing a high-risk procedure to repair an extensive thoracoabdominal aortic aneurysm. It's not for those in prison, pregnant, extremely ill ('moribund'), with ruptured aneurysms, needing urgent repairs, or with blood clotting issues that prevent safe placement of a CSF drain.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo endovascular thoracoabdominal aortic aneurysm repair with either prophylactic or selective cerebrospinal fluid drain placement
Follow-up
Participants are monitored for the onset of spinal cord ischemia and other complications post-operatively
Treatment Details
Interventions
- Cerebrospinal Fluid Drain Placement
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alabama at Birmingham
Lead Sponsor
University of Massachusetts, Worcester
Collaborator
The University of Texas Health Science Center, Houston
Collaborator