Counseling + Medicine for Depression/Anxiety in Cardiac Surgery Patients
What You Need to Know Before You Apply
What is the purpose of this trial?
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing cardiac surgery (compared with usual care), while examining implementation outcomes.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is the combination of counseling and medicine safe for humans?
How is Behavioral Activation Therapy different from other treatments for depression and anxiety in cardiac surgery patients?
Behavioral Activation Therapy is unique because it focuses on helping patients engage in activities that improve their mood, rather than primarily using medication or traditional talk therapy. This approach is particularly beneficial for cardiac surgery patients as it can be tailored to their physical recovery process, encouraging gradual re-engagement with life activities that can enhance both mental and physical health.678910
What data supports the effectiveness of this treatment for depression and anxiety in cardiac surgery patients?
Research shows that psychological interventions, like those in the study, can reduce depression and anxiety in cardiac surgery patients, especially when delivered by trained professionals and after surgery. Additionally, hypnotherapy has been found to significantly reduce anxiety and depression in similar patient groups.68101112
Who Is on the Research Team?
Simon Haroutounian, PhD, MSc
Principal Investigator
Washington University School of Medicine
Are You a Good Fit for This Trial?
This trial is for adults aged 60 or older who are about to have major heart surgery and are showing signs of depression or anxiety. They must be able to communicate in English and not have severe cognitive issues, acute suicidal thoughts, or previous participation in similar studies.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Perioperative Treatment
Behavioral activation and medication optimization begin perioperatively
Postoperative Treatment
Behavioral activation and medication optimization continue for 3 months postoperatively
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Behavioral Activation
- Medication Optimization
Behavioral Activation is already approved in United States, China, European Union for the following indications:
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Who Is Running the Clinical Trial?
Washington University School of Medicine
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator