HR-A for Prostate Cancer

Phase-Based Progress Estimates
University of Florida Health Proton Therapy Institute, Jacksonville, FLProstate CancerHR-A - Radiation
18 - 100
What conditions do you have?

Study Summary

This trial is testing a new way to give radiation therapy to patients with high-risk prostate cancer. The new method features hypofractionation and a simultaneous integrated boost to the magnetic resonance imaging (MRI) identified intraprostatic tumor (IPT).

Eligible Conditions
  • Prostate Cancer

Treatment Effectiveness

Study Objectives

1 Primary · 6 Secondary · Reporting Duration: 60 months after the end of radiation therapy

Year 5
Assessment of local persistence or local recurrence
Cumulative rate of biochemical failure at 5 years after the end of treatment.
Rate of distant metastases five years after end of radiation therapy
Month 60
Cumulative rate of late toxicity observed between 90 days and 5 years after end of treatment.
Day 90
Cumulative rate of acute toxicity observed between day 1 of treatment and 90 days after treatment.
Year 5
Rate of change in sexual, bowel, and urinary function from baseline measurement to 5 years after end of treatment.

Trial Safety

Trial Design

2 Treatment Groups

HR-A (High-risk A)
1 of 2
HR-B (High-risk B)
1 of 2

Experimental Treatment

100 Total Participants · 2 Treatment Groups

Primary Treatment: HR-A · No Placebo Group · N/A

HR-A (High-risk A)
Experimental Group · 1 Intervention: HR-A · Intervention Types: Radiation
HR-B (High-risk B)
Experimental Group · 1 Intervention: HR-B · Intervention Types: Radiation

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 60 months after the end of radiation therapy

Who is running the clinical trial?

University of FloridaLead Sponsor
1,261 Previous Clinical Trials
699,340 Total Patients Enrolled
10 Trials studying Prostate Cancer
3,818 Patients Enrolled for Prostate Cancer
Curtis M Bryant, MD, MPHPrincipal InvestigatorUniversity of Florida Health Proton Therapy Institute
1 Previous Clinical Trials
1 Trials studying Prostate Cancer

Eligibility Criteria

Age 18 - 100 · Male Participants · 11 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:

Frequently Asked Questions

Does this research project include elderly participants?

"This medical trial is inviting applicants aged 18 and up, but no older than 100 years old." - Anonymous Online Contributor

Unverified Answer

Does my condition fulfill the requirements for participation in this experiment?

"Individuals suffering from adenocarcinoma and between the ages of 18 to 100 are eligible for this medical trial. A maximum of one hundred patients may be admitted into the study." - Anonymous Online Contributor

Unverified Answer

Are there any openings for enrolment in this clinical experiment?

"Affirmative. Evidenced by the portal, this medical trial is currently recruiting participants, with 100 needed from 1 site. It was initially published on September 24th 2018 and recently edited on September 2nd 2022." - Anonymous Online Contributor

Unverified Answer

What is the scope of participants in this research endeavor?

"Affirmative. According to, the medical trial posted on September 24th 2018 is currently looking for volunteers. One hundred participants are needed from a single research centre." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.