ATVV for Infant Behavior

1
Effectiveness
1
Safety
Banner University Medical Center - Tucson, Tucson, AZ
+2 More
ATVV - Behavioral
Eligibility
18+
Female
Eligible conditions
Infant Behavior

Study Summary

A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity

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Eligible Conditions

  • Infant Behavior
  • Relation, Parent-Child
  • Behavior, Maternal

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether ATVV will improve 1 primary outcome and 5 secondary outcomes in patients with Infant Behavior. Measurement will happen over the course of 84 +/- 7days from birth (approximately 3 months after birth).

Month 3
Mother-Infant Synchrony, Gaze and Affect
Mother-Infant Synchrony, Vocalization and Touch
Month 3
Oxytocin peptide
Oxytocin receptor gene DNA methylation reflecting epigenetic marks
Oxytocin receptor gene expression
Oxytocin receptor protein

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

Attention control
Behavioral ATVV intervention

This trial requires 250 total participants across 2 different treatment groups

This trial involves 2 different treatments. ATVV is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Behavioral ATVV intervention
Behavioral
A multi-sensory behavioral intervention that includes auditory, tactile, visual and vestibular (ATVV) stimulation contingent upon infant cues.
Attention control
Behavioral
An attention control group that receives education on safe infant care and the same amount of attention as the intervention group.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline at 31weeks +/- 2 weeks gestation and every 28 days +/- 7 days from birth to 3 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly baseline at 31weeks +/- 2 weeks gestation and every 28 days +/- 7 days from birth to 3 months for reporting.

Who is running the study

Principal Investigator
A. B.
Prof. Aleeca Bell, Associate Professor
University of Arizona

Closest Location

Banner University Medical Center - Tucson - Tucson, AZ

Eligibility Criteria

This trial is for female patients aged 18 and older. There are 9 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Gestational diabetes is a form of diabetes that is found in pregnant women show original
is associated with having a life expectancy of less than 62 years The ACE survey is associated with a life expectancy of less than 62 years if you score greater than or equal to 2. show original
The expectant mother will deliver a healthy baby who is at least 37 weeks old. show original
The expectant mother will deliver a single infant. show original
An individual must be 18 years old or older in order to be considered an adult. show original
Pregnant
Nulliparous (previous miscarriage(s) and/or abortion(s) acceptable)
I can speak and read English and Spanish. show original
Expect to give birth to a healthy infant. show original

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can behavior, maternal be cured?

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In a recent study, findings suggest that maternal behavior might be amenable to change in a short period of therapy, which should be followed up with continued treatment for at least 6 months.

Unverified Answer

What are the signs of behavior, maternal?

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There is a wide range of possible signs of behavior, maternal. All such observations should be evaluated in terms of their possible significance. Knowledge of one or more of these signs may lead to improvements in assessing behavior problems, improving parental counseling, or managing infant-parent relationships.

Unverified Answer

What is behavior, maternal?

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Behavioral problems in the home and school are common among parents with children with autism. Children of depressed parents can be at increased risk for depression themselves.

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What are common treatments for behavior, maternal?

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Treatment of children with ADHD may be guided by a combination of pharmacotherapy, behavioral treatment, and parent involvement. Cognitive behavior therapy can be utilized effectively for the treatment of child behavior patterns in the face of maternal depression. Antidepressant medication, specifically selective serotonin reuptake inhibitors, may be an effective treatment for maternal depression. Other psychological treatment styles can be effectively utilized to treat other symptomatology, while incorporating treatment elements from these other styles.

Unverified Answer

What causes behavior, maternal?

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Maternal behavior and social environment appear to be the two most influential factors in behavior development. The effects of maternal behavior can be seen in children as early as 6 months of age. The effect of maternal behavior on child behavior is especially apparent as the child grows into adolescence, and the associations between maternal behaviors and child adjustment are particularly marked in the aftermath of a behavioral problem when the child is about 14 to 18 months old. Results from a recent clinical trial suggest that the child's development through adolescence is best described as a series of "developmental milestones" linked by a common process, a "behavioral-developmental framework" that is sensitive to environmental stressors.

Unverified Answer

How many people get behavior, maternal a year in the United States?

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A national survey of medical clinic visits for maternal behaviors found that there were an estimated 1.7 to 1.8 million people, representing approximately 1 of 10 of the U.S. population visiting a medical clinic for a maternal behavior.

Unverified Answer

What is the primary cause of behavior, maternal?

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Maternal behavior is a product of a complex gene-environment continuum where genes and environments in combination influence maternal behavior. Because the most important and consistent environmental variables influencing the quality of life of the child are the quality of the mother-child relationship, the effects of maternal behavior on behavior are probably mediated in an interaction with child-rearing style and parenting.

Unverified Answer

Have there been any new discoveries for treating behavior, maternal?

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If we all continue our efforts in [behavior, paternal] treatment and research, we will one day be able to help our mothers with postpartum depression and other [behavior, paternal] problems.\n

Unverified Answer

Is atvv safe for people?

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Atvuvat, when administered as part of a comprehensive opioid addiction prevention program is safe and effective at decreasing heroin use and increasing other indicators of good behavioral change. While the small numbers in this study prevented conclusive analysis and highlight the need for randomized control trials, these data suggest that AAV-1 is an effective treatment that deserves further study.

Unverified Answer

What are the latest developments in atvv for therapeutic use?

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A systematic review of the most recent literature is provided below; more should be done to study the safety, efficacy, effects and costs of many of the newer A2A subtype agents that have arisen since 2011, including the potential of combined with one, or several older A2A antagonists.

Unverified Answer

What does atvv usually treat?

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Many health professionals have prescribed atvv to women with postpartum symptoms in the past. The lack of research to determine the appropriateness of prescribing atvv at this time may lead others to begin prescribing atvv without adequate justification.

Unverified Answer

Who should consider clinical trials for behavior, maternal?

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Clinicians and patients should be aware of the possible negative psychosocial effects of participation in a clinical trial of behavior modification therapies. Results from a recent paper of this study indicate that women should be aware of the possibility that participation in a clinical trial of behavior therapies will alter these practices and may lead to negative psychosocial effects on women.

Unverified Answer
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