80 Participants NeededMy employer runs this trial

Pectoral Block for Pain Control in Breast Reduction

PD
Overseen ByPatrick Dugom, MD
Age: 18+
Sex: Female
Trial Phase: Phase 4
Sponsor: Carilion Clinic
Must be taking: Analgesics, NSAIDs
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

A reduction mammoplasty is a commonly performed procedure for patients with symptomatic macromastia. The procedure involves removing breast parenchyma for an overall reduction in breast size and to alleviate patient symptoms, such as back/neck pain, rashes in the inframammary fold, and bra strap indentation. It is well documented in the literature that this procedure has a statistically significant reduction in patient symptoms. Postoperatively, it has been within the norm to prescribe narcotics in order to alleviate post-procedural pain. Recently, however, the research realm has advocated a non-narcotic multimodal pain control (MMPC) approach to minimize narcotic usage. Narcotic use is associated with increased costs in the healthcare system due to reported heightened pain scores for extended duration, constipation, nausea, vomiting, opiate dependence among other factors associated with increased morbidity.

The goal of this study is to determine if PECs II (pectoral block type II) block alone is non-inferior to the standard multimodal pain control with narcotics for postoperative pain reduction in breast reduction.

Who Is on the Research Team?

AC

Anthony Capito, MD

Principal Investigator

Carilion Clinic

Are You a Good Fit for This Trial?

Inclusion Criteria

I am having breast reduction surgery.
I am a woman between 18 and 74 years old.
* Stable breast size for at least 1 year
See 6 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants undergo breast reduction surgery with either PECs II block or standard multimodal pain control

1 day
1 visit (in-person)

Postoperative Monitoring

Participants are monitored for pain control and narcotic usage through surveys on days 1, 3, and 7 post-surgery

1 week
Surveys on days 1, 3, and 7

Follow-up

Participants are monitored for safety and effectiveness after treatment

2 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Pectoral II Nerve Block

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: PEC II block groupExperimental Treatment2 Interventions
Group II: Control groupActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Carilion Clinic

Lead Sponsor

Trials
85
Recruited
15,400+