Vevye + Flarex for Dry Eye Syndrome

(FLARE-VEV Trial)

Age: 18+

Sex: Any

Trial Phase: Phase 4

Sponsor: Canyon City Eyecare

Must not be taking: Antihistamines, Antidepressants

Disqualifiers: Uncontrolled systemic disease, Glaucoma, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Prior Safety Data This treatment has passed at least one previous human trial

Compensation: Varies

Number of Visits: 5

Duration: 1 month

What You Need to Know Before You Apply

What is the purpose of this trial?

This study evaluates the safety and efficacy of combination therapy with Vevye (cyclosporine ophthalmic solution) and Flarex (fluorometholone acetate ophthalmic suspension) in adults with moderate to severe dry eye disease. Participants receive Vevye twice daily and Flarex four times daily, with outcomes assessed over a 1-month period.

Are You a Good Fit for This Trial?

Inclusion Criteria

I am an adult with moderate to severe dry eye and can give informed consent.

No eligibility criterion provided.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

1 visit (in-person)

Baseline

Initial assessment and start of treatment with Vevye and Flarex

1 day

1 visit (in-person)

Treatment

Participants receive Vevye twice daily and Flarex four times daily

1 month

Multiple visits (Day 3, Week 1, Month 1)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Flarex
• Vevye

How Is the Trial Designed?

Group I: Combination Therapy Arm Experimental Treatment 2 Interventions

Participants receive Vevye (cyclosporine ophthalmic solution) twice daily and Flarex (fluorometholone acetate ophthalmic suspension) four times daily.

Who Is Running the Clinical Trial?

Canyon City Eyecare

Lead Sponsor

Trials

1

Recruited

60+