Your session is about to expire
← Back to Search
Blood Pressure Medications for High Blood Pressure in Obesity
Study Summary
This trial will compare the effects of two different blood pressure medications on heart function.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2012 Phase 4 trial • 1012 Patients • NCT01176968Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- I am between 18 and 70 years old.My BMI is 30 or higher with at least one health issue, or it's 25 or higher with at least two.My fasting triglycerides are over 150 mg/dL and my HDL is low.I have a history of heart disease, including heart attack, failure, irregular heartbeat, or stroke.I have high blood pressure controlled by one medication and am willing to stop it for 2 weeks for a study.My blood pressure is between 120/80 and 159/99 mmHg and untreated.My kidney function is reduced.Your EKG shows certain heart changes that may not be safe for this study.I have been diagnosed with or treated for diabetes.Your blood potassium level is higher than 5.2 mEq/L.Your blood sugar levels are slightly higher than normal when fasting or your A1c test shows slightly elevated average blood sugar levels.My blood pressure is between 120-139/80-89 or 140-159/90-99 mmHg and untreated.
- Group 1: Chlorthalidone with potassium chloride
- Group 2: Eplerenone
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there any additional investigations involving Eplerenone?
"As of now, 39 clinical trials are researching the efficacy of Eplerenone. Of these studies, 6 have reached phase 3. Although most experiments related to this drug occur in Nagoya, Aichi, there are 132 worldwide testing sites available."
To what medical conditions is Eplerenone most commonly prescribed?
"Eplerenone is frequently employed to reduce edema, and can also be effective for treating kidney diseases, terminal state maladies, and myocardial infarction."
Is this research project currently accessible to participants?
"Per the information posted on clinicaltrials.gov, this medical investigation is in search of subjects to further their research. The trial was inaugurated December 1st 2020 and last updated February 28th 2022."
Could I potentially partake in this clinical endeavor?
"This clinical trial requires 80 participants aged between 18 to 70 years old, who are currently affected by metabolic syndrome. Eligibility criteria also stipulates that all patients must fall in the aforesaid age range."
How many test subjects are currently participating in the experiment?
"Indeed, the information available on clinicaltrials.gov states that this investigation is actively scouting for participants. It was initially posted in December 2020 and most recently updated at the end of February 2022; it aims to gather 80 individuals from a single site."
Is the elderly demographic being considered for inclusion in this experiment?
"Participants hoping to be considered for this medical trial must fall within the age bracket of 18-70. On the other hand, there are 300 studies available for minors and 1745 trials catered towards seniors."
What risks are associated with the ingestion of Eplerenone?
"Data indicates that eplerenone has been approved for use, thus receiving a safety score of 3."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Share this study with friends
Copy Link
Messenger