Treatment for Pneumonia

Waitlist Available · Any Age · All Sexes · Cape Girardeau, MO

This study is evaluating whether a new way to remove secretions from the airway of patients on mechanical ventilation can be effective and safe.

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About the trial for Pneumonia

Eligible Conditions
Ventilations, Mechanical · Pneumonia

Treatment Groups

This trial involves a single treatment. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.


This trial is for patients born any sex of any age. There are 3 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
are at less risk for ventilator-associated pneumonia than patients intubated with an endotracheal tube with an internal diameter of less than 7.0 mm show original
Patients who receive medical care in an adult intensive care unit setting are often very sick show original
Patients who have been intubated and mechanically ventilated for at least 12 hours
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: pre-extubation
Screening: ~3 weeks
Treatment: Varies
Reporting: pre-extubation
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: pre-extubation.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Treatment will improve 1 primary outcome and 1 secondary outcome in patients with Pneumonia. Measurement will happen over the course of pre-extubation.

work of breathing
endotracheal tube patency

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can pneumonia be cured?

Can pneumonia be cured? If the pneumonia is the result of an infection of a distant site or if blood tests and chest film show characteristic features of pneumonia, the patient should be treated, even if the radiology shows a 'chest radiograph of pneumonia'.

Anonymous Patient Answer

What are the signs of pneumonia?

Symptoms that may help the physician decide whether a patient has pneumonia include mummification, shortness of breath, rapid breathing and chest pain. Fever and white blood cell count elevation are usually present in patients with pneumonia.

Anonymous Patient Answer

How many people get pneumonia a year in the United States?

About 30 million Americans are currently hospitalized for a pneumonia-related condition each year, so over two thirds of hospital stays for pneumonia could be avoided if pneumonia admissions were more accurately monitored and contained in the pneumonia care continuum. Moreover, by better tracking pneumonia admissions, we might be able to reduce unnecessary hospitalizations, unnecessary medical treatment, inappropriate use of antibiotics, and inappropriate use of non-antibiotics that pose unnecessary risks.

Anonymous Patient Answer

What is pneumonia?

Severe pneumonia manifests as an acute onset of cough and fever. Most people recover quickly if treated. Mortality is high with about 14 in 100 requiring hospitalization. Acute-phase reactants, such as C-reactive protein and erythrocyte sedimentation rate (ESR), have poor accuracy when tested for fever.\n\nA review on the latest update of pneumonia and clinical practice recommendations provided by the Centers for Disease Control and Prevention (CDC) states:\n- "Clinical judgment is usually sufficient to determine whether or not an individual patient has pneumonia and which antibiotics should be used".

Anonymous Patient Answer

What causes pneumonia?

Pneumonia is most commonly caused by viruses, and the bacteria causing it can vary by location. The major risk factors for pneumonia are smoking, poor nutrition, alcoholism, poor immune function, and poor dental care. Pneumonia is also associated with certain underlying medical situations. Diagnosis is confirmed by demonstrating the pathogen in a sample of pulmonary secretions, through blood tests or nucleic acid amplification tests. Antibiotics can be prescribed.

Anonymous Patient Answer

What are common treatments for pneumonia?

Pneumonia can be treated with antibiotic therapy. A small percentage of cases may be improved by an antiviralytic agent. Antibiotics are usually required to treat pneumonia because of the number of bacterial infections that are typically associated with respiratory problems. Antibiotics are often effective in treating all causative organisms that are typically found in respiratory secretions. Clinicians should always consider other possible causes when working with patients with pneumonia because the management is often complicated by the multiple factors that have the potential to have a negative impact on the outcome. For patients with atypical pneumonia, the addition of azithromycin may be more desirable.

Anonymous Patient Answer

Does treatment improve quality of life for those with pneumonia?

Results from a recent clinical trial demonstrated that HRQL improves 3 months after treatment for CAP. These improvements may persist longer after treatment is completed, but further investigations are needed to determine the extent of improvements after one year.

Anonymous Patient Answer

Is treatment typically used in combination with any other treatments?

The [interferon in combination with ribavirin has no advantage over treatment with either intervention alone in patients with or at high risk of developing HCV genotype 3 infections over the first 24 weeks of treatment, as measured by the rate of sustained virologic response or sustained viral control] (

Anonymous Patient Answer

Is treatment safe for people?

For common illnesses such as pneumonia for which treatment is only indicated for people with poor judgment and high risk of dying, those in the 'no treatment' group appear to have not experienced worse outcomes. This would represent a risk to those patients' life and quality of life. This was not accounted for in these data.

Anonymous Patient Answer

What is the latest research for pneumonia?

[To get the best treatment for pneumonia, we are encouraged to visit websites that tell us a great deal about how recent clinical trials have shown new treatment options. For example, we can visit EudraCT( and choose a clinical trial in Lancet(, which can help us find interesting trials.

Anonymous Patient Answer

Have there been other clinical trials involving treatment?

Given the number of small clinical trials and low confidence values, a new clinical trial (with a size that is statistically and clinically significant; with only one arm and with multiple end points) should be undertaken.

Anonymous Patient Answer

What does treatment usually treat?

One of the most common features of pneumonia in the SGR was that the majority of patients (65 %) with moderate to severe pneumonia received treatment, but only 15 % received guideline-recommended treatment.

Anonymous Patient Answer
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