Study Summary
This trial compares semaglutide with insulin glargine in people with type 2 diabetes, looking at how well they control blood sugar levels. Participants will take one medicine or the other for 47 weeks and have 9 clinic visits, 15 phone/video calls, and 1 home visit. They will also wear a sensor measuring blood sugar for 2 periods of 10 days.
- Obesity
- Type 2 Diabetes
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 13 Secondary · Reporting Duration: At end of treatment (week 40)
Trial Safety
Safety Progress
Side Effects for
Trial Design
4 Treatment Groups
Insuline glargine U100 (titrated)
1 of 4
Insuline glargine (titrated)
1 of 4
Insuline glargine U100 (reduced) + semaglutide
1 of 4
Insuline glargine (reduced) + semaglutide
1 of 4
Active Control
Experimental Treatment
568 Total Participants · 4 Treatment Groups
Primary Treatment: Semaglutide · No Placebo Group · Phase 3
Trial Logistics
Logistics
Other reimbursement is provided
Other forms of reimbursement are provided for this trial.
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 4 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Tennessee | 65.6% |
| Ohio | 9.4% |
| Texas | 6.3% |
| Other | 18.8% |
How old are they?
| 18 - 65 | 100.0% |
What site did they apply to?
| Novo Nordisk Investigational Site | 81.8% |
| Other | 18.2% |
What portion of applicants met pre-screening criteria?
| Did not meet criteria | 76.7% |
| Met criteria | 23.3% |
How many prior treatments have patients received?
| 0 | 56.5% |
| 1 | 8.7% |
| 2 | 8.7% |
| 3+ | 26.1% |
Why did patients apply to this trial?
- "Trying to get my diabetes under control."
- "I want to get my type 2 diabetes under control and lower my A1C"
- "I am also on Trulicity. I really have to loose some weight. I need help."
- "Have prediabetes. Father died at 48 yrs. Old from diabetes complications"
- "I’m tired of having diabetes and the complications that come along with it."
What questions have other patients asked about this trial?
- "What does the trial do?"
How responsive is this trial?
Average response time
- < 2 Days
Most responsive sites:
- Novo Nordisk Investigational Site: < 48 hours
Typically responds via
| Phone Call | 71.4% |
| 28.6% | |
Frequently Asked Questions
Has Semaglutide been given the green light by the FDA?
"Semaglutide was given a 3 because, although it is only in Phase 3 trials, there is already some data supporting its efficacy and multiple rounds of data suggesting that it is safe." - Anonymous Online Contributor
Are people with the disease currently being accepted into this trial?
"Correct, the listing on clinicaltrials.gov indicates that this trial is still recruiting patients. The study was first posted on 8/29/2022 and edited for the last time on 11/10/2022. In total, 568 participants are needed from 49 different locations." - Anonymous Online Contributor
Are there a significant number of hospitals conducting this trial across North America?
"Currently, this study is being conducted in 49 different centres, which are situated in cities such as Chicago, Los Angeles and West Hills. To make the process more convenient for patients, it is advised to select a clinical trial site that is located near you." - Anonymous Online Contributor