This trial is testing a combination of two drugs, phentermine and topiramate, to see if it can help adolescents with severe obesity keep off lost weight.
10 Primary · 0 Secondary · Reporting Duration: Baseline, 1 day of Randomization, Week 26 and Week 52 visits.
3 Treatment Groups
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Meal Replacement Therapy
1 of 3
1 of 3
143 Total Participants · 3 Treatment Groups
Primary Treatment: Meal Replacement Therapy · Has Placebo Group · Phase 2
Who is running the clinical trial?
Age 12 - 18 · All Participants · 2 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Are young adults eligible for this kind of research?
"According to the inclusion criteria, this trial is for patients aged 12-18. Out of the 893 total clinical trials, 216 are for minors and 677 are for elderly patients." - Anonymous Online Contributor
Are there any health risks associated with Meal Replacement Therapy?
"While Phase 2 trials are not as reliable in terms of patient safety data, Meal Replacement Therapy showed some signs of being safe in clinical trials and was given a score of 2." - Anonymous Online Contributor
How many total participants are in this research?
"That is correct. If you visit clinicaltrials.gov, you will see that this trial has an open call for participants. The listing was created on August 4th 2021 and the most recent update occurred on October 8th 2022. They are looking to enroll 143 people at a single site." - Anonymous Online Contributor
Are there any available appointments for this research project?
"That is correct, the listing on clinicaltrials.gov says that this study is open for recruitment. This particular trial was first advertised on August 4th, 2021 and was last updated October 28th, 2022. They are looking to enroll 143 patients at a single site." - Anonymous Online Contributor
What are people using Meal Replacement Therapy to improve?
"Meal Replacement Therapy is a common treatment for tonic-clonic seizures. It can also help patients experiencing lipidemia, lennox gastaut syndrome (lGS), and type 2 diabetes mellitus." - Anonymous Online Contributor
Does this research build on other scientific investigations of Meal Replacement Therapy?
"There are currently 20 clinical trials underway that focus on studying Meal Replacement Therapy. 3 of those active trials are in their third and final Phase. The majority of these trials for Meal Replacement Therapy originated in Sherbrooke, Quebec; however, there are a total of 36 locations running studies related to this treatment option." - Anonymous Online Contributor