This trial is evaluating whether Treatment will improve 1 primary outcome, 2 secondary outcomes, and 1 other outcome in patients with Triple Negative Breast Neoplasms. Measurement will happen over the course of Baseline and at surgery (after 20 weeks).
This trial requires 185 total participants across 4 different treatment groups
This trial involves 4 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 2 and have already been tested with other people.
"Breast cancer is a complex disease and there are many different treatments available, but they all can be classified into six main categories of treatment: surgery, radiation therapy, chemotherapy, hormonal therapy, targeted therapy and immunotherapy.\n\nSurgery often consists of removing the lump through a surgical procedure called lumpectomy.\n\nRadiation therapy uses X-rays and sometimes also gamma rays to treat the cancer cells.\n\nChemotherapy or chemo drugs are used to kill cancer cells. There are many different kinds of chemotherapy and they are used either alone or together with other treatment. Types of chemotherapy include:\n- Alkylating agents (e.g." - Anonymous Online Contributor
"There is no single 'right' treatment for any patient. Each individual has different needs and expectations. It is important to remember that treatment needs to address all aspects of the patient’s health. Treatments need to address the patient’s medical history, family history, social support network, and her physical abilities. Treatments also need to take into account the psychological, emotional, and spiritual needs of the patient. Breast cancer treatment guidelines are evolving and changing over time. The available data do not allow us to definitively state which treatment is ‘best’ for any specific patient. We only know about what treatments work best for certain patients with certain types of breast cancer." - Anonymous Online Contributor
"With all of these studies, we cannot answer this question definitively. However, based on previous studies, there appears to be no difference between treatments and placebos when tested against two clinic trials. More studies need to be conducted to determine the efficacy of any of these alternative treatments." - Anonymous Online Contributor
"Treatment improved QOL among women with breast cancer. Women reported better QOL when they received multimodal therapy compared with those receiving chemotherapy alone. Higher education and higher income appear to be associated with better QOL. Health care providers should provide information about benefits and risks of adjuvant treatment." - Anonymous Online Contributor
"A large proportion of women who were considered for clinical trial enrollment did not complete requests to enroll in clinical trials. Many patients received inconsistent treatment due to lack of information regarding clinical trial status. Recent findings suggest that clinical trial notification and enrollment may improve patient outcomes." - Anonymous Online Contributor
"No significant relationship was observed between the risk of developing BC and the total number of pregnancies, parity, breastfeeding and age at first pregnancy. However, women who had used hormonal contraception were more likely to develop BC." - Anonymous Online Contributor
"Treatment works by removing the cancer cells from the body when there are no more viable cancer cells left. As the cancer evolves, it becomes either non-malignant or malignant again. When the cancer exists only in the blood, it will get removed without any treatment. However, if the cancer remains malignant, then treatment must be given to remove all the cancer cells from the body. There are many different types of cancer treatments. But most of them focus on removing the cancer cells from the body and that's why they are called “removal” treatments." - Anonymous Online Contributor
"Women with no known risk factors account for more than 95% of new cases of breast cancer annually. About 5% of women who develop breast cancer will be diagnosed before age 45 years; most of these will receive adjuvant therapy. No significant differences were observed in the adjusted incidence rates of breast cancer among black women, white women, and Hispanic women over the period 1979-1993." - Anonymous Online Contributor
"We found no evidence of significant differences between women who developed metastases within five years versus those who did not develop metastases within five years following diagnosis; however, our results were limited by small numbers in each group. To confirm our results with larger numbers of patients, additional studies are needed." - Anonymous Online Contributor
"Although surgery has always been considered the only curative option for early breast cancer, we believe that the results reported here have led to a shift towards the use of systemic treatment in addition to surgery. Systemic therapy may improve the disease-free survival but does not appear to guarantee cure. Further studies are required to develop the best combination of therapies for use in patients with advanced breast cancer." - Anonymous Online Contributor
"Breast cancer treatment outcomes are improving; however, younger women do not fare as well compared to those older than 50 years old. Breast cancer remains the leading cause of cancer-related deaths among women aged 20-39 years." - Anonymous Online Contributor