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Zanubrutinib + Obinutuzumab + Venetoclax for Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia
Study Summary
This trial is testing a new combo treatment for CLL/SLL to see how effective it is at getting rid of disease.
- Chronic Lymphocytic Leukemia
- Small Lymphocytic Leukemia
Eligibility Criteria
Inclusion Criteria
You will be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Awards & Highlights
Trial Design
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Who is running the clinical trial?
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- Group 1: BOVEN regimen
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this study popular in North America?
"There are 8 medical centres conducting this trial. These locations include Memorial Sloan Kettering Westchester in Harrison, Memorial Sloan Kettering Cancer Center in New York, and Massachusettsn New Yoing Cancer Center in New York, and Massachusetts General Hospital (Data Collection and Specimen Analysis) in Boston."
Are there any risks associated with Venetoclax?
"While there is some data supporting its safety, Venetoclax received a score of 2 because this is only a Phase 2 trial and no efficacy has been proven yet."
What are some common reasons why Venetoclax is given to patients?
"Venetoclax is not only useful for treating small lymphocytic lymphoma, but can also be employed when managing lymphoid leukemiac lymphoma, but can also be employed when managing lymphoid leukemia and certain types of lymphoma."
What is the total number of participants for this research?
"Yes, clinicaltrials.gov currently lists this trial as active and recruiting patients. The study was first posted on February 22nd, 2019, and was most recently updated on September 9th, 2022. They are looking for a total of 127 participants across 8 different locations."
What are some previous examples of research using Venetoclax?
"Venetoclax was first studied in 2012 at CHU de Dijon. As of now, 118 clinical trials have been completed while 323 are still ongoing. Many of the active studies are based out of Harrison, New York."
Can patients still sign up for this trial?
"The clinical trial is currently looking for 127 patients at 8 different sites, according to the latest data from clinicaltrials.gov. This study was originally posted on February 22nd, 2019 and was most recently updated on September 9th, 2020."
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