← Back to Search

Neurologic Music Therapy for Parkinson's Disease

N/A

Recruiting

Led By Isabelle Buard, PhD

Research Sponsored by University of Colorado, Denver

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Fine motor impairments (if available, scores 2 and higher on the UPDRS motor examination part III.23 and 24)

Age 45 to 85

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline and 5 weeks

Awards & highlights

Study Summary

This trial will test whether Neurologic Music Therapy can help improve fine motor movements for adults with Parkinson's Disease.

Who is the study for?

Adults aged 45-85 with Parkinson's Disease, experiencing fine motor impairments, and stable on medication for at least a month can join. Excluded are those with other forms of parkinsonism, inability to move fingers or hands, involvement in other music therapy studies, lack of insurance coverage for Occupational Therapy, advanced Parkinson's (stage 4+), metal implants affecting MEG/MRI data or safety concerns, and dementia.Check my eligibility

What is being tested?

The trial is testing Neurologic Music Therapy (NMT) against Music Supported Therapy (MST) and standard Occupational Therapy (OT). It aims to see if NMT improves fine motor skills in Parkinson’s patients by using musical instruments and rhythm exercises compared to MST and OT.See study design

What are the potential side effects?

Since the interventions involve music therapy and occupational activities rather than drugs or invasive procedures, significant side effects are not anticipated. However, participants may experience fatigue or frustration during the sessions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have difficulty with tasks that require small, precise movements.

Select...

I am between 45 and 85 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline and 5 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline and 5 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and 5 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Clinical Outcome: Motor 1 (change in the Grooved Pegboard Test)

Magnetoencephalography

Mechanistic Outcome: Neurophysiology 2 (change in auditory-motor functional connectivity using Magnetoencephalography)

+1 more

Secondary outcome measures

Clinical Outcome: Motor 2 (change in the Unified Parkinson Disease Rating Scale Part III)

Clinical Outcome: Motor 3 (change in the Finger-Thumb opposition from the Neurological Evaluation Scale)

Quality of Life (QOL) Outcome: QOL 2 (change in the Clinical Global Impression - Improvement Scale)

+1 more

Trial Design

4Treatment groups

Experimental Treatment

Active Control

Group I: Neurologic Music Therapy (NMT)Experimental Treatment1 Intervention

Neurologic Music Therapy is a 5-week intervention using different musical instruments and auditory cues to specifically improve fine motor movements.

Group II: Occupational Therapy (OT)Active Control1 Intervention

Standard of care occupational therapy uses traditional motor training.

Group III: Waitlist ControlActive Control1 Intervention

Participants assigned to the waitlist-control condition will not immediately receive services. The no-treatment duration for these participants is yoked to the amount of time their respective NMT- and OT-condition participants receive services (5 weeks). After the wait period, these participants will then be randomized to receive either NMT, MST or OT sessions.

Group IV: Music Supported Therapy (MST)Active Control1 Intervention

Music Supported Therapy uses musical instruments to train fine motor movements.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of Colorado, DenverLead Sponsor

1,738 Previous Clinical Trials

2,149,426 Total Patients Enrolled

National Center for Complementary and Integrative Health (NCCIH)NIH

833 Previous Clinical Trials

669,353 Total Patients Enrolled

Isabelle Buard, PhDPrincipal InvestigatorUniversity of Colorado, Denver

Media Library

Neurologic Music Therapy Clinical Trial Eligibility Overview. Trial Name: NCT03049033 — N/A

Parkinson's Disease Research Study Groups: Neurologic Music Therapy (NMT), Occupational Therapy (OT), Waitlist Control, Music Supported Therapy (MST)

Parkinson's Disease Clinical Trial 2023: Neurologic Music Therapy Highlights & Side Effects. Trial Name: NCT03049033 — N/A

Neurologic Music Therapy 2023 Treatment Timeline for Medical Study. Trial Name: NCT03049033 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacant spots available for participation in this research?

"Affirmative. According to the clinicaltrials.gov listing, this experiment is actively recruiting participants since it was first published on April 26th 2017 and most recently edited on January 19th 2022. The researchers are looking for 100 test subjects from a single medical centre."

Answered by AI

What is the ultimate aim of this experiment?

"This clinical trial will be conducted over a Baseline and 5 week period, with the primary Quality of Life (QOL) Outcome being an assessment of change in the 39-Item Parkinson's disease. Secondary QOL outcomes include evaluations of changes in Hospital Anxiety and Depression Scale as well as Clinical Global Impression - Improvement Scale. The second motor outcome for this study is an analysis of Unified Parkinson disease Rating Scale Part III variation."

Answered by AI

What steps do I need to take in order to participate in this experiment?

"In order to join this clinical trial, participants must possess parkinson disease and be between the ages of 45 and 85. This particular research endeavour is enrolling a total of 100 volunteers."

Answered by AI

How many participants are being recruited for this clinical trial?

"Affirmative. Clinicaltrials.gov has data that confirms recruitment for the clinical trial, which was first introduced on April 26th 2017 and most recently revised January 19th 2022. The aim is to find 100 patients from one medical centre."

Answered by AI

Is this research protocol allowing those aged 45 and above to participate?

"To participate in this trial, patients must be between 45 and 85 years old. Additionally, there are 27 trials for those under 18 and 485 for those over the age of 65."

Answered by AI

Recent research and studies

TrialsJournal

Randomized Controlled Trial of Neurologic Music Therapy in Parkinson’s Disease: Research Rehabilitation Protocols for Mechanistic and Clinical Investigations

Buard, Isabelle, Lucas Lattanzio, Rebekah Stewart, Sarah Thompson, Kristin Sjoberg, Karen Hookstadt, Meghan Morrow, et al.. 2021. “Randomized Controlled Trial of Neurologic Music Therapy in Parkinson’s Disease: Research Rehabilitation Protocols for Mechanistic and Clinical Investigations”. Trials. Springer Science and Business Media LLC. doi:10.1186/s13063-021-05560-7.

clinicaltrials.govStudy

NMT for Parkinson's Disease

2017. "NMT for Parkinson's Disease". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03049033.

All > Parkinsons Disease > Parkinson