Doxercalciferol (GZ427397) for Neoplasm Metastasis
Safety and Efficacy of Hectorol in Pediatric Patients With Chronic Kidney Disease Stage 3 and 4 With Secondary Hyperparathyroidism Not Yet on Dialysis
See full descriptionAbout the trial for Neoplasm Metastasis
Treatment Groups
This trial involves 2 different treatments. Doxercalciferol (GZ427397) is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 3 and have had some early promising results.
Eligibility
This trial is for patients born any sex aged 65 and younger. There are 5 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Doxercalciferol (GZ427397) will improve 1 primary outcome and 4 secondary outcomes in patients with Neoplasm Metastasis. Measurement will happen over the course of Baseline up to Week 12.
Patient Q & A Section
What are the chances of developing neoplasm metastasis?
The incidence of the development of PM metastasis is higher than that of OSCC or NPC and it is also a significant cause of the death in patients.
What does doxercalciferol (gz427397) usually treat?
It was concluded that the study found no difference between the drugs in terms of efficacy, side effect profile, and pain management. The study found differences in cost between calcipotriol, etidronate and etidronic acid.
What is the average age someone gets neoplasm metastasis?
The average age that a cancer patient gets metastasis is 62 years (average 63). In most people, that is more than the average age of all Americans. It is, therefore, worthwhile searching for cancer and the neoplasm metastasis. Of course, if you do have cancer, check with your doctor.
Have there been other clinical trials involving doxercalciferol (gz427397)?
To our knowledge there are no other clinical trials which have evaluated the use of doxercalciferol as a first line therapy for patients with metastatic breast cancer.
Who should consider clinical trials for neoplasm metastasis?
A significant number of practitioners may be interested in clinical trials of neoplasm metastasis, but further research is needed to provide evidence-based recommendations for patient selection.
What are common treatments for neoplasm metastasis?
In summary, according to our review, most commonly used treatments for neoplasm metastasis are not specifically approved by the FDA or are not well-studied by the FDA and may be only partially effective.
What causes neoplasm metastasis?
It should not be overlooked that neoplasm metastases are caused by neoplasmal genetic and other factors other than tumor cells. Moreover, neoplasm metastasis is influenced by metastatic target tissues. Lymph node metastasis in breast cancer is one of the most common reasons for neoplasm metastasis.
What is neoplasm metastasis?
Neoplasm metastasis is the result of cancer cells that have been released, by shedding of cells, from their primary tumors into the blood or distant organs. It can cause a range of disorders, from chronic pain to death. Neoplasm metastasizing is most often diagnosed by CT and MRI examinations. The process of metastasis is also called'migration' of neoplastic cells.
How many people get neoplasm metastasis a year in the United States?
Around 928,000 neoplasm metastases were diagnosed in the United States annually. Most of these cases (60%) were caused by cancers. Nearly 40% were caused by breast and prostate cancers, while other malignancies were responsible for approximately 10% of metastases. The most common cancer diagnosed in conjunction with neoplasm metastasis was non-Hodgkin's lymphoma, making neoplasm metastasis the second most common cause of cancer-related deaths in children, adolescent, and adult males, after leukemia diagnoses.
What are the signs of neoplasm metastasis?
Different sites of metastasis have different characteristics and signs, and metastasis in distant organs tends to take longer to develop and thus is often not discovered before death from the primary neoplasm has occurred. The signs of metastases are similar to the primary neoplasm; however, distant metastases tend to be more solid and painless.
Does neoplasm metastasis run in families?
In a recent study, findings indicate that family history and age determine the probability of metastatic spread. Those with a positive family history and older age are at higher risk of metastasis. In contrast, most patients with a negative family history do not present with disseminated disease when analyzed by age.