ACTivity for Depression

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Brown University, Providence, RI
Depression+1 More
ACTivity - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will compare two different treatments for low-active adults with elevated depressive symptoms - group-based acceptance and commitment therapy for physical activity (ACT; ACTivity) or a standard PA intervention plus relaxation training (Relaxercise). ACTivity is used to treat Depression. It has previously been approved by the FDA for a different condition. No patients in this trial will receive a placebo.

Eligible Conditions

  • Depression
  • Physical Inactivity

Treatment Effectiveness

Study Objectives

1 Primary · 2 Secondary · Reporting Duration: Baseline, Mid-Treatment (4 weeks) Post-Treatment (8 weeks), 6-months

Week 8
Change in Acceptance of physical activity-related distress (Physical Activity Acceptance Questionnaire)
Change in Discomfort intolerance (Discomfort Intolerance Scale)
Change in Physical activity enjoyment (PACES questionnaire)
Change in Physical activity values clarification (valuing questionnaire)
Change in Physical activity-related motivation (Treatment Self-Regulation Questionnaire - Exercise Version)
Change in Self-report physical activity (Godin)
Change in Self-reported depression symptoms (CES-D)
Week 8
Change in Accelerometry
Post-Treatment (8 weeks)
Change in Group cohesion questionnaire
Week 12
Change in Client satisfaction questionnaire
Week 1
Change in Credibility and expectancy questionnaire

Trial Safety

Trial Design

2 Treatment Groups

Relaxercise
1 of 2
ACTivity
1 of 2
Active Control
Experimental Treatment

60 Total Participants · 2 Treatment Groups

Primary Treatment: ACTivity · No Placebo Group · N/A

ACTivity
Behavioral
Experimental Group · 1 Intervention: ACTivity · Intervention Types: Behavioral
Relaxercise
Behavioral
ActiveComparator Group · 1 Intervention: Relaxercise · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, mid-treatment (4 weeks) post-treatment (8 weeks), 6-months
Closest Location: Brown University · Providence, RI
Photo of rhode island 1Photo of rhode island 2Photo of rhode island 3
2004First Recorded Clinical Trial
10 TrialsResearching Depression
78 CompletedClinical Trials

Who is running the clinical trial?

National Center for Complementary and Integrative Health (NIH)UNKNOWN
Brown UniversityLead Sponsor
406 Previous Clinical Trials
515,121 Total Patients Enrolled
28 Trials studying Depression
11,113 Patients Enrolled for Depression
Da M Wil, Ph.D.Principal InvestigatorBrown University School of Public Health

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have elevated depressive symptoms (CES-D score of greater than or equal to 10).
You have low-intensity PA (less than 60 minutes per week of moderate intensity PA).

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.