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CoolCurve vs. ATX-101 for Upper Back Fat

N/A
Waitlist Available
Led By Murad Alam, MD
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and day 90
Awards & highlights

Study Summary

This trial is looking at whether cryolipolysis or ATX-101 is more effective for treating upper back fat. If you live in the Chicago area and meet the criteria, you may be eligible to participate.

Who is the study for?
This trial is for adults over 18 in good health with mild to moderate upper back fat, living in the Chicago area. They must understand and consent to participate. Excluded are those with cold-induced diseases, scar issues, pregnancy, breastfeeding, neurological disorders affecting cooperation or understanding of the protocol, and anyone on antiplatelet/anticoagulant therapy or with coagulation disorders.Check my eligibility
What is being tested?
The study compares cryolipolysis (CoolCurve) and ATX-101 (deoxycholic acid) for reducing upper back fat. Participants will have one side of their back treated with CoolCurve and the other side with ATX-101 randomly. The goal is to see which treatment is more effective.See study design
What are the potential side effects?
Possible side effects may include reactions at the treatment site such as redness, swelling, pain or tenderness; these are common after both cryolipolysis and injections like ATX-101.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and day 90
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and day 90 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in fat measurements from baseline to Day 90.

Side effects data

From 2015 Phase 3 trial • 55 Patients • NCT02123134
71%
Injection site bruising
71%
Injection site pain
61%
Injection site swelling
50%
Injection site anaesthesia
29%
Injection site nodule
18%
Injection site oedema
14%
Injection site induration
14%
Injection site erythema
7%
Pain in jaw
7%
Dysphonia
7%
Skin tightness
4%
Headache
100%
80%
60%
40%
20%
0%
Study treatment Arm
Placebo
ATX-101 (Deoxycholic Acid) Injection

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Deoxycholic AcidExperimental Treatment1 Intervention
Group II: CyrolipolysisActive Control1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
ATX-101
2008
Completed Phase 3
~330

Find a Location

Who is running the clinical trial?

Northwestern UniversityLead Sponsor
1,585 Previous Clinical Trials
917,197 Total Patients Enrolled
Murad Alam, MDPrincipal InvestigatorNorthwestern University
69 Previous Clinical Trials
2,546 Total Patients Enrolled

Media Library

Upper Back Fat Clinical Trial 2023: ATX-101 Highlights & Side Effects. Trial Name: NCT03284034 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any vacancies remaining in this experiment for participants?

"Unfortunately, this clinical trial is no longer recruiting. Initially posted on November 27th 2017 and last edited March 2nd 2022, the search for participants has come to an end. However, those interested in similar studies can still find 1 study searching for patients with upper back fat and 4 trials actively enrolling individuals seeking ATX-101 treatment."

Answered by AI

What is the aggregate sum of individuals who are enrolled in this medical experiment?

"This clinical trial has ended its enrollment phase, having been posted on the 27th of November 2017 and last amended in March 2022. However, there are 1 study still looking for candidates with upper back fat issues as well as 4 other trials recruiting participants to assess ATX-101's efficacy."

Answered by AI

Are any other studies underway that involve ATX-101?

"Currently, there are 4 clinical trials for ATX-101 in operation across the world. None of these trials have reached Phase 3 yet but they can be found at 9 different locations, mostly based around South Brisbane, Queensland."

Answered by AI

Who else is applying?

What state do they live in?
West Virginia
Texas
Ohio
How old are they?
18 - 65
What site did they apply to?
Northwestern University Department of Dermatology
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
Recent research and studies
clinicaltrials.govStudy
Cryolipolysis Versus ATX-101 (Deoxycholic Acid) for Upper Back Fat
Murad Alam 2017. "Cryolipolysis Versus ATX-101 (Deoxycholic Acid) for Upper Back Fat". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03284034.
All > Kybella
~7 spots leftby Dec 2025
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