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HIPEC for Advanced Stomach Cancer
Study Summary
This trial looks at whether a certain type of chemotherapy can help to increase the expression of a protein called PD-L1 in stomach cancer that has spread to the abdomen.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have another cancer, but it won't affect this trial's treatment.I am allergic to medications similar to cisplatin or Mitomycin C.You cannot be part of any other experimental treatments or studies at the same time.I am not pregnant or breastfeeding.My heart function is classified as class 2B or better according to NYHA.I have recovered from side effects of previous cancer treatments, except for hair loss.My cancer has spread to organs like the liver, lungs, bone, or brain.I do not have any unmanaged ongoing illnesses.I am 18 years old or older.I have stomach or peritoneal cancer and finished chemo for 2-4 months.Your doctor expects you to live for more than 3 months.My kidney function is within the safe range for the trial.I had hepatitis C but have been treated and cured, or I am currently being treated with an undetectable viral load.I agree to use birth control during and up to 4 months after the study.My organs and bone marrow are working well.I am HIV positive, on treatment, and my viral load has been undetectable for the last 6 months.My hepatitis B virus load is undetectable with treatment.I can take care of myself but might not be able to do heavy physical work.I have not had any cancer other than skin cancer in the last 5 years.
- Group 1: Drug Administration Period
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Has Mitomycin been cleared by the FDA?
"There is some data supporting the safety of Mitomycin, but none indicating that it is an effective treatment, so it received a score of 2."
How many people are included in this research?
"Yes, that is accurate. The clinical trial's website indicates that the research is ongoing and still recruiting patients. The 21 participants are needed at a single location."
Are volunteers currently being accepted for this research?
"That is correct. The information available on clinicaltrials.gov does show that the trial is currently recruiting patients. According to the website, the study was posted on November 11th, 2019 and updated January 19th, 2022. They are looking for a total of 21 participants from 1 site."
How does this new research on Mitomycin compare to other findings in the field?
"745 trials are currently underway to study Mitomycin. Of these, 292 are in Phase 3. Most of the research is conducted in Shanghai, but there are 44334 locations running studies for this treatment."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
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