Combination Wound Care for Hidradenitis Suppurativa
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new method to heal wounds caused by hidradenitis suppurativa (HS), a condition that results in painful, recurring skin bumps and tunnels. The study focuses on using special wound dressings made from methylene blue, gentian violet, and ovine forestomach (sheep stomach tissue) to evaluate the speed and effectiveness of wound healing. Individuals with HS who have non-healing wounds or draining abscesses may be suitable candidates for this trial. As a Phase 2 trial, the research measures the treatment's effectiveness in an initial, smaller group of participants.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is there any evidence suggesting that this treatment is likely to be safe for humans?
Research has shown that a combination of methylene blue, gentian violet, and special wound dressings made from sheep stomach lining is generally safe for treating wounds. These dressings help manage hidradenitis suppurativa, a painful skin condition, by keeping wounds clean and reducing bacteria. Described as non-cytotoxic, the product does not harm living cells, suggesting it is well-tolerated by patients.
Studies indicate that these dressings can be worn for a week without causing irritation, demonstrating their safety. So far, no major side effects have been reported with these dressings, making them a promising option for people dealing with this challenging condition.12345Why do researchers think this study treatment might be promising for HS?
Researchers are excited about this treatment for Hidradenitis Suppurativa (HS) because it combines methylene blue, gentian violet, and ovine forestomach wound dressings, offering a potentially innovative approach. Unlike traditional options like antibiotics and surgery, this combination targets HS lesions with unique active ingredients that have antimicrobial properties. The use of ovine forestomach wound dressings is particularly interesting as it may enhance healing by providing a natural scaffold for tissue repair. This multifaceted approach could lead to more effective and faster relief for individuals suffering from this painful condition.
What evidence suggests that this combination wound care treatment might be effective for Hidradenitis Suppurativa?
Research has shown that a combination of methylene blue, gentian violet, and special dressings made from sheep stomach can effectively treat wounds in people with hidradenitis suppurativa (HS). In this trial, participants will receive these dressings, which possess antibacterial properties that help reduce infections in wounds. Studies have found that this type of wound care can be used for a week without slowing the healing process. Patients have reported an improved quality of life with these dressings, as they help HS wounds heal faster. Overall, these treatments are safe and non-toxic, making them a promising option for those with HS.13567
Who Is on the Research Team?
Rita Pichardo, MD
Principal Investigator
Wake Forest University Health Sciences
Are You a Good Fit for This Trial?
This trial is for adults over 18 with hidradenitis suppurativa (HS) who have non-healing wounds or draining abscesses/nodules. It's not open to those under 18 or without an HS diagnosis.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive methylene blue, gentian violet, and ovine forestomach wound dressings to HS lesions
Follow-up
Participants are monitored for wound healing and pain assessment
What Are the Treatments Tested in This Trial?
Interventions
- methylene blue, gentian violet, and ovine forestomach wound dressings
Find a Clinic Near You
Who Is Running the Clinical Trial?
Wake Forest University Health Sciences
Lead Sponsor