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CMV-MVA Triplex Vaccine for Cytomegalovirus
Study Summary
This trial will test a new vaccine for CMV. 60 people will get the vaccine and 30 will get a placebo. The vaccine will be given as two injections, four weeks apart.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have heart disease or diabetes.I plan to use immune system boosting drugs during the study.I have had symptoms of CMV disease in the last year.I haven't used immunomodulators, HIV vaccines, chemotherapy, or experimental drugs recently.I have active hepatitis B or C.I am between 18 and 65 years old.I haven't taken any anti-CMV drugs in the last 14 days.I haven't had a serious illness needing treatment in the last 2 weeks.I have been taking statin medication consistently for at least 12 weeks.I have not received an MVA-based vaccine in the last year.I haven't changed my HIV medication in the last 12 weeks.I haven't had blood products or immune globulin in the last 3 months.I have been on continuous antiretroviral therapy for at least 48 weeks.I am on blood thinners or have a bleeding disorder that prevents me from getting muscle injections.
- Group 1: Vaccine Group
- Group 2: Placebo Group
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does the inclusion criteria for this study extend to individuals beyond 45 years of age?
"The guidelines for inclusion in this clinical trial necessitate that the age of participants must be between 18 and 65 years old."
What is the upper limit for participants in this clinical research?
"Affirmative. Clinicaltrials.gov reports that this experiment is actively searching for participants, with the initial posting falling on November 2nd 2021 and the most recent update occurring June 20th 2022. The medical trial aims to enlist 90 individuals from 12 sites."
What are the eligibility requirements to join this clinical experiment?
"This clinical trial is searching for 90 participants aged between 18 and 65 with a pre-existing HIV infection. These are the baseline requirements to be eligible for enrolment."
Are there any vacancies left in this clinical research project?
"Affirmative. According to clinicaltrials.gov, this study is currently enrolling 90 patients from 12 different sites and has been accepting candidates since November 2nd 2021 with its most recent update on June 20th 2022."
What additional experiments have been conducted concerning the Vaccine Group?
"Vaccine Group was initially studied in 2015 at Dana-Farber Cancer Institute. To date, 18378 trials have been completed and 16 studies are still ongoing - many of these being carried out from Los Angeles, California."
What evidence is there that Vaccine Group provides a secure treatment option?
"The safety of Vaccine Group was rated a 2, since the Phase 2 trial only showed preliminary evidence for its safety but not efficacy."
Are there multiple venues in Canada dispatching this research?
"This trial has 12 medical centres that are actively recruiting, with locations in Los Angeles, Boston and Aurora. For patient convenience, it is advised to select the closest participating site for minimal travel requirements when partaking in this study."
Who else is applying?
What site did they apply to?
What portion of applicants met pre-screening criteria?
Why did patients apply to this trial?
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