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Xenon-129 MRI for Pulmonary Disease

Phase 2

Recruiting

Led By Giles Santyr, PhD

Research Sponsored by The Hospital for Sick Children

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year

Awards & highlights

Study Summary

This trial is looking at whether a new MRI technique called Xenon-129 MRI can help show differences in the lungs of people with cystic fibrosis or asthma, compared to healthy people.

Eligible Conditions

Cystic Fibrosis
Asthma

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Significant differences in lung function between CF and healthy group and asthma and healthy group for ventilation defect percent (VDP) measurement

Trial Design

3Treatment groups

Active Control

Group I: AsthmaActive Control3 Interventions

Participants with asthma ages 8 and older.Participants with inhale hyperpolarized xenon-129 which is used as a contrast agent for lung imaging. Participants will undergo magnetic resonance imaging and lung clearance index.

Group II: Cystic FibrisosActive Control3 Interventions

Participants with cystic fibrosis ages 8 and older.Participants with inhale hyperpolarized xenon-129 which is used as a contrast agent for lung imaging. Participants will undergo magnetic resonance imaging and lung clearance index.

Group III: HealthyActive Control3 Interventions

Healthy Participants ages 8 and older. Participants with inhale hyperpolarized xenon-129 which is used as a contrast agent for lung imaging. Participants will undergo magnetic resonance imaging and lung clearance index.

Do I qualify?Apply below to find out

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Who is running the clinical trial?

The Hospital for Sick ChildrenLead Sponsor

689 Previous Clinical Trials

6,945,391 Total Patients Enrolled

23 Trials studying Cystic Fibrosis

2,124 Patients Enrolled for Cystic Fibrosis

Giles Santyr, PhDPrincipal InvestigatorThe Hospital for Sick Children

6 Previous Clinical Trials

183 Total Patients Enrolled

1 Trials studying Cystic Fibrosis

70 Patients Enrolled for Cystic Fibrosis

Media Library

Asthma Clinical Trial Eligibility Overview. Trial Name: NCT02740868 — Phase 2

Cystic Fibrosis Research Study Groups: Asthma, Cystic Fibrisos, Healthy

Cystic Fibrosis Clinical Trial 2023: Asthma Highlights & Side Effects. Trial Name: NCT02740868 — Phase 2

Asthma 2023 Treatment Timeline for Medical Study. Trial Name: NCT02740868 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the enrollment number for this scientific experiment?

"Yes, the information on clinicaltrials.gov confirms that this trial is presently seeking participants, having posted as of August 1st 2015 and updated on October 24th 2022. A total of 30 patients are needed to complete enrollment at a single medical site."

Answered by AI

Have any other investigations focused on Cystic Fibrosis been conducted?

"Currently, 15 clinical trials exist to investigate the efficacy of treatments for Cystic fibrosis. Of those studies, none are in Phase 3. Locations running these experiments range from Pennsylvania's Philadelphia all the way to 21 other sites across the globe."

Answered by AI

To what degree is Cystic Fibrosis hazardous to one's health?

"Given that we are currently in Phase 2 of the trial, which has generated limited data on Cystic fibrosis' safety but no evidence for its efficacy, our team at Power assigned it a score of 2."

Answered by AI

Are there any enrollment opportunities available for this trial?

"According to clinicaltrials.gov, this medical study is still open for recruitment; the trial was first posted on August 1st 2015 and recently modified on October 24th 2022."

Answered by AI