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LYR-210 for Chronic Sinusitis
Study Summary
This trial is designed to compare the efficacy of two treatments by randomly assigning patients to receive either one or the other. The trial will be conducted at multiple centers, will involve at least three phases, will be blinded (meaning that the patients will not know which treatment they are receiving), and will be controlled (meaning that there will be a control group of patients who receive no treatment).
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2021 Phase 2 trial • 71 Patients • NCT04041609Trial Design
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Who is running the clinical trial?
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- I have been diagnosed with CRS.I have never had sinus surgery.I have been diagnosed with or am being diagnosed for chronic sinusitis.I have had symptoms like nasal blockage or loss of smell for over 3 months.My CRS symptoms significantly affect my daily life.I have used steroid nasal sprays for at least 4 weeks.My average symptom score is relevant.
- Group 1: Sham procedure control
- Group 2: LYR-210
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there any risks associated with LYR-210?
"LYR-210 safety has been supported by numerous rounds of clinical data, resulting in a Power team score of 3."
Is this trial prominent in Canadian hospitals?
"This study is being conducted in 30 different centres across the nation, with sites located in major cities such as Los Angeles, Frisco and Cleveland. If you enroll in this trial, be sure to pick a location that is close to reduce travel time and expenses."
How many people are going to be enrolled in this clinical trial?
"That is correct. The clinicaltrials.gov website has the latest information on this trial, which was first posted on May 13th, 2022 and updated October 25th, 2022. There are 180 participants needed in total, with 30 different locations hosting the trial."
Are there any positions still open in this experiment?
"The most recent information available on clinicaltrials.gov reveals that this trial is still ongoing and actively recruiting patients. The study was first posted on May 13th, 2020 and was last updated on October 25th, 2020. They are looking for a total of 180 participants across 30 different sites."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
Why did patients apply to this trial?
How responsive is this trial?
Average response time
- < 2 Days
Typically responds via
Most responsive sites:
- Berkson Medical: < 48 hours
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