SBRT for Bone Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This research study is studying a form of radiation therapy called stereotactic body radiation therapy or SBRT as a possible treatment for Cancer that has spread to the spine or other bone
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it does mention that you cannot be on active systemic therapies (treatments that affect the entire body) at the same time as the trial. Hormonal therapies are allowed.
Is SBRT generally safe for humans?
How is SBRT treatment different from other treatments for bone cancer?
SBRT (Stereotactic Body Radiation Therapy) is unique because it delivers a high dose of radiation precisely to the target area in one or a few sessions, minimizing damage to surrounding healthy tissue. This is different from conventional radiation therapy, which typically involves multiple lower-dose treatments and may affect more of the surrounding area.24678
What data supports the effectiveness of the treatment Stereotactic Body Radiation Therapy (SBRT) for bone cancer?
Research suggests that SBRT, a precise radiation therapy, can effectively manage bone metastases by delivering high doses of radiation to the target area while sparing nearby healthy tissues. It has shown potential in improving pain and local control in patients with bone metastases compared to conventional radiotherapy.69101112
Who Is on the Research Team?
Tracy Balboni, MD MPH
Principal Investigator
Dana-Farber Cancer Institute
Are You a Good Fit for This Trial?
This trial is for adults over 18 with bone cancer that has spread to the spine or other bones, but not more than three places. They should be in good enough health to sign consent and have a life expectancy of over 3 months. Pregnant women, those with blood cancers, recent other cancers (except certain skin cancers and cervical cancer in situ), or who can't lie still for treatment are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive Stereotactic Body Radiation Therapy (SBRT) to up to 3 sites of disease occurring in the bone or spine
Follow-up
Participants are monitored for safety and effectiveness after treatment, including quality of life assessments
Long-term Follow-up
Participants are monitored for progression-free survival and overall survival
What Are the Treatments Tested in This Trial?
Interventions
- Stereotactic Body Radiation Therapy (SBRT)
Stereotactic Body Radiation Therapy (SBRT) is already approved in United States, European Union, Canada, Japan for the following indications:
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Who Is Running the Clinical Trial?
Dana-Farber Cancer Institute
Lead Sponsor