ADINA vs. High Flow Nasal Cannula for Breathing Difficulties in Premature Babies
Trial Summary
What is the purpose of this trial?
This study is to evaluate the feasibility of using a pressure limited nasal cannula system instead of a high flow nasal cannula system in the management of premature babies with respiratory distress.
Will I have to stop taking my current medications?
The trial information does not specify whether participants need to stop taking their current medications.
What data supports the effectiveness of the treatment Adaptive Dynamic Inspiratory Nasal Apparatus (ADINA) and High Flow Nasal Cannula for breathing difficulties in premature babies?
Research shows that using a high flow nasal cannula (a tube that delivers warm, moist air through the nose) can help premature babies breathe better by improving their lung function and reducing their effort to breathe. This treatment has been effective in supporting breathing in preterm infants, especially after they have been taken off a ventilator.12345
Is the high flow nasal cannula safe for premature babies?
How is the ADINA treatment different from other treatments for breathing difficulties in premature babies?
The Adaptive Dynamic Inspiratory Nasal Apparatus (ADINA) is unique because it adapts to the baby's breathing patterns, potentially offering more personalized support compared to the High Flow Nasal Cannula (HFNC), which provides a constant flow of air. This adaptability may help reduce the effort of breathing more effectively in premature infants.128910
Research Team
Mitchell R Goldstein, MD
Principal Investigator
Loma Linda University Health
Eligibility Criteria
This trial is for premature babies in the NICU, weighing 400-500 grams and needing extra oxygen. It's not for those with heart issues, allergies to adhesives, severe facial deformities, infections like pneumonia or sepsis, very fragile skin, or uncontrolled breathing problems.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either the ADINA device or high flow nasal cannula system for respiratory support
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Adaptive Dynamic Inspiratory Nasal Apparatus
- High flow Nasal Canula
Find a Clinic Near You
Who Is Running the Clinical Trial?
Loma Linda University
Lead Sponsor