This trial is evaluating whether Epidural Stimulation will improve 2 primary outcomes, 3 secondary outcomes, and 1 other outcome in patients with Spinal Cord Injuries. Measurement will happen over the course of Baseline to 12 months.
This trial requires 20 total participants across 2 different treatment groups
This trial involves 2 different treatments. Epidural Stimulation is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are in Phase 2 & 3 and have had some early promising results.
The most common injuries were high force trauma, penetrating injuries, and falls from heights. The cause of SCI is complicated by the fact that a different injury pattern occurs in each individual case, but for every individual case, a specific cause-related injury pattern for the injury has been suggested. What causes SCIs?
The most common treatment for spinal cord injuries is hospitalization, often following an accident. Most patients recover, and physical therapy is not considered a treatment. There is no evidence to prove that orthotics help maintain posture. There is a lack of consensus about the use of casts and braces for post-acute spinal cord injuries. Androsterone was found to be beneficial in improving muscle strength and endurance. There is no evidence to support the use of surgery for spinal cord injuries and there have been no successful attempts to restore full movement after spinal cord injuries.
Each year, around 2,900 people are diagnosed with a cervical spinal cord injury and 5,100 people are diagnosed with a thoracic spinal cord injury. For those who recover, the chance of achieving full independence is about 50-60%. For those who do not, the chance is about 20-30%.
There are a wide variety of subtle neurologic signs of spinal cord injury. These signs are often difficult to detect with the nonneurologic clinician or, in most cases, in the acute phase of the injury. The clinical manifestations of spinal cord injury are very complex, in addition to multiple etiologies.
Overall, most SCI patients and their families are able to deal with their injuries. However, some patients have severe emotional distress or depression. Depression is hard to treat and may be untreatable. We recommend that SCI patients be screened for depression with self-report inventories.
Spinal cord injuries (SCI) can cause a wide range of disabling conditions such as motor, sensory, urinary and bowel disturbances. The impact is profound on the person and on their families.\n
A significant number of SCI patients are eligible for clinical trials. There is a potential to identify treatments for SCI. The cost and time of implementing such studies is high. At this early stage, it is unclear if such studies lead to a real improvement in care.
Injuries occur during adolescence, particularly for males. Because more than one in 6 individuals over the age of 60 is affected by an SCI, the current rate has the potential to be one of the most important reasons why SCIs are becoming a growing health issue.
This family study found that SCIs run in families. This is the first family-based study of SCI and highlights the importance of genetic predisposition in the aetiology of SCI.
The findings from this study demonstrated that patients with a history of spinal cord injury can achieve a dynamic walking pattern using the exoskeletal aid. This enables patients to participate in conventional physical therapy, thereby increasing their participation and function in rehabilitation.
Participation of a patient with incomplete cervical spondylotic myelopathy in a 6-month exoskeleton-assisted functional training program resulted in a greater gain in walking ability, functional independence, and patient satisfaction than with a placebo-controlled group. The study suggests that a rehabilitation program for patients with incomplete cervical spondylotic myelopathy can lead to clinically useful functional gains.
Walking with exoskeletal assistive devices can be tolerated by at least 79% of people with SCI over 3 months post injury. Results from a recent clinical trial does not support the current debate about the safety of exoskeleton assisted walking vs. conventional gait training for people with SCI. Further research, however, is warranted to establish the effects of long-term use of this technology on walking speed and quality of life for people with SCI.