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Ixabepilone + Temsirolimus for Advanced Cancer
Study Summary
This trial is testing ixabepilone and temsirolimus to see if they are effective and have manageable side effects in treating patients with solid tumors.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2021 Phase 1 & 2 trial • 24 Patients • NCT03010358Trial Design
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Who is running the clinical trial?
Media Library
- I do not have any severe illnesses that my doctor says are not under control.My heart condition severely limits my daily activities.I am currently breastfeeding.I am of childbearing age and do not plan to use birth control.I am immunocompromised due to conditions other than corticosteroid use, including HIV.My cancer has spread, cannot be surgically removed, and standard treatments have failed.My blood clotting time is normal and I'm not on warfarin.My INR level is between 2.0 and 3.0 while on warfarin.My brain metastases have been stable for over 6 months without seizures or steroids.I can take care of myself and am up and about more than half of my waking hours.I haven't had biologic therapy in the last 28 days.I had radiation therapy less than 28 days ago.I have had a heart attack in the last 6 months or have heart failure needing constant treatment.I have high cholesterol.I haven't had chemotherapy in the last 28 days.I haven't taken Mitomycin C or nitrosoureas in the last 42 days.There is a known treatment for my condition that could cure me or extend my life.I have moderate to severe numbness or pain in my hands or feet.I am not taking strong medication that affects liver enzymes or it can be changed.My triglyceride levels are high.I have not had immunotherapy in the last 28 days.I still have side effects from my last chemotherapy.I am not currently on any experimental treatments.I have had no more than two treatments for my cancer after it spread, except for hormone therapy.More than a quarter of my bone marrow has been exposed to radiation.I am not on any experimental drugs for my cancer.My cancer can be monitored but not measured.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
- Group 1: Treatment (ixabepilone, temsirolimus)
Frequently Asked Questions
What risks do participants of the Pharmacological Study potentially face?
"There is only limited clinical data attesting to the safety of this pharmacological study, so it received a rating of 1."
How many participants are receiving care within this trial?
"This clinical trial is not presently enrolling patients. It was originally added to the database on June 27th 2011 and recently modified on September 20th 2022. If you're looking for other active studies, there are 5 trials accepting adult solid-tumor participants and 159 research initiatives recruiting people who want to take part in pharmacological investigations."
What therapeutic purposes does Pharmacological Study typically serve?
"Pharmacological Study is a common remedy for coughing, along with treating joint discomfort, upper respiratory tract infection and seborrheic dermatitis."
Are there any other examples of Pharmacological Study being tested in prior clinical studies?
"At present, there are 159 studies running that research Pharmacological Study. Of those active trials, 18 have reached Phase 3. Whilst the majority of Pharmocological Study related investigations originate from Cincinnati, Ohio - 1971 sites worldwide are conducting trials involving this treatment modality."
Are there any current opportunities for participation in this research?
"Unfortunately, no further participants are being recruited for this study. It was posted on June 27th 2011 and the most recent edit to the protocol occurred on September 20 2022. On the other hand, there are 5 trials currently accepting patients with adult solid neoplasm and 159 studies in which pharmacological research is underway that have opportunities for involvement."
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