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Air Filtration

HEPA Filters for Cardiometabolic Health

N/A

Recruiting

Led By Junfeng Zhang, PhD

Research Sponsored by University of Southern California

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at the baseline and immediately after each of the 6-month interventions

Awards & highlights

Study Summary

This trial tests if using HEPA filters can improve heart and metabolic health by reducing air pollution.

Who is the study for?

This trial is for people aged 65-84 living in Los Angeles County who are overweight (BMI ≥ 25 kg/m2 historically), non-smokers for at least a year, have Wi-Fi at home, and speak English or Spanish. It's not for those with active cancer treatment, plans to move soon, certain health conditions, homes unsuitable for air purifiers or already equipped with HEPA filters.Check my eligibility

What is being tested?

The study tests if using HEPA filters in the home can improve heart and metabolic health by reducing fine particle pollution indoors. Participants will be randomly assigned to use either a real HEPA filter or a fake one without knowing which they have.See study design

What are the potential side effects?

Since this trial involves the use of air filters rather than medication, there are no direct side effects from interventions like you would expect with drugs. However, changes in air quality could potentially affect respiratory symptoms.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at the baseline and immediately after each of the 6-month interventions

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at the baseline and immediately after each of the 6-month interventions

This trial's timeline: 3 weeks for screening, Varies for treatment, and at the baseline and immediately after each of the 6-month interventions for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in HOMA-IR

Change in HbA1c

Secondary outcome measures

Change in blood pressure

Change in continuously monitored glucose level

Change in fasting glucose

+2 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: HEPA first and shamExperimental Treatment2 Interventions

This group of participants will be assigned an intervention of HEPA filters with the capacity to reduce PM2.5 levels at their residence for 6 months. After 6-month wash-out period, will be assigned to sham filters for 6 months.

Group II: Sham first and HEPAPlacebo Group2 Interventions

This group of participants will be assigned an intervention of sham filters without the capacity to reduce PM2.5 levels at their residence for 6 months. After 6-month wash-out period, will be assigned to HEPA filters for 6 months.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

HEPA filter

2016

N/A

~180

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Southern CaliforniaLead Sponsor

906 Previous Clinical Trials

1,596,124 Total Patients Enrolled

Duke UniversityOTHER

2,364 Previous Clinical Trials

3,420,590 Total Patients Enrolled

Junfeng Zhang, PhDPrincipal InvestigatorDuke University

5 Previous Clinical Trials

376 Total Patients Enrolled

Media Library

HEPA filter (Air Filtration) Clinical Trial Eligibility Overview. Trial Name: NCT05718245 — N/A

Cardiometabolic Syndrome Research Study Groups: HEPA first and sham, Sham first and HEPA

Cardiometabolic Syndrome Clinical Trial 2023: HEPA filter Highlights & Side Effects. Trial Name: NCT05718245 — N/A

HEPA filter (Air Filtration) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05718245 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there an age limit to join this medical research experiment?

"The specified age range for admission into this clinical trial is 65 to 84 years old. Additionally, there are 7 separate trials designed specifically for either people under 18 or those over the age of 65."

Answered by AI

Are enrollment slots currently available for this scientific experiment?

"As indicated on clinicaltrials.gov, the recruitment period for this trial is now closed - having been initially posted on January 31st 2023 and updated most recently on February 7th 2023. However, 10 other medical trials are actively seeking suitable candidates at present."

Answered by AI

Is my profile suitable to join this experiment?

"This trial is looking to include 52 participants that are aged between 65 and 84 and have been affected by air pollution."

Answered by AI

What are the projected results from this trial?

"This study will evaluate Change in HbA1c over a six-month period. Secondary outcomes include the difference between baseline and fasting insulin, discrepancies between LDL, HDL, VLDL, triglycerides and total cholesterol levels at both time points, as well as any changes to systolic or diastolic blood pressure measurements post-intervention."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

HEPA, PM2.5, and Cardiometabolic Health

Zhanghua Chen 2023. "HEPA, PM2.5, and Cardiometabolic Health". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05718245.