~200 spots leftby Nov 2026

APAP for Obstructive Sleep Apnea in Mental Illness

Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: University of California, San Diego
No Placebo Group

Trial Summary

What is the purpose of this trial?

This trial is testing a treatment called Positive Airway Pressure (PAP) for adults with serious mental illnesses like schizophrenia and bipolar disorder who also have sleep apnea. PAP treatment uses a machine to help keep the airways open during sleep by providing a steady stream of air through a mask. The study aims to see if this treatment can improve cognitive function and overall health in these patients over several months. Positive Airway Pressure (PAP) is the standard and most effective treatment for obstructive sleep apnea (OSA).

Eligibility Criteria

This trial is for adults aged 40-70 with serious mental illnesses like schizophrenia or bipolar disorder, who may also have or be at risk for obstructive sleep apnea. Participants should not have other major psychiatric conditions and must not be under conservatorship.

Inclusion Criteria

I am at risk for or have been diagnosed with obstructive sleep apnea.
I have been diagnosed with schizophrenia, schizoaffective disorder, or bipolar disorder.
You have never had a serious mental illness in your life.
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Treatment Details

Interventions

  • Automatic Positive Airway Pressure (APAP) (Positive Airway Pressure Device)
Trial OverviewThe study is testing the use of Automatic Positive Airway Pressure (APAP) machines to treat obstructive sleep apnea in individuals with serious mental illnesses, assessing how it might improve their cognitive function.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Automatic Positive Airway Pressure (APAP) deviceExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, San Diego

Lead Sponsor

Trials
1,215
Recruited
1,593,000+