APAP for Obstructive Sleep Apnea in Mental Illness
Trial Summary
What is the purpose of this trial?
This trial is testing a treatment called Positive Airway Pressure (PAP) for adults with serious mental illnesses like schizophrenia and bipolar disorder who also have sleep apnea. PAP treatment uses a machine to help keep the airways open during sleep by providing a steady stream of air through a mask. The study aims to see if this treatment can improve cognitive function and overall health in these patients over several months. Positive Airway Pressure (PAP) is the standard and most effective treatment for obstructive sleep apnea (OSA).
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you are already receiving treatment for obstructive sleep apnea, you may not be eligible to participate.
What data supports the effectiveness of the treatment Automatic Positive Airway Pressure (APAP) for Obstructive Sleep Apnea in people with mental illness?
Research shows that treating obstructive sleep apnea (OSA) with Continuous Positive Airway Pressure (CPAP), which is similar to APAP, can improve cognitive function and reduce psychiatric symptoms in people with schizophrenia. This suggests that APAP might also help improve sleep and mental health in people with mental illness who have OSA.12345
Is APAP safe for treating obstructive sleep apnea in people with mental illness?
How does the APAP treatment for obstructive sleep apnea in mental illness differ from other treatments?
APAP (Automatic Positive Airway Pressure) is a unique treatment for obstructive sleep apnea because it automatically adjusts the air pressure to the patient's needs throughout the night, unlike CPAP (Continuous Positive Airway Pressure) which provides a constant pressure. This can be particularly beneficial for individuals with mental illness, as it may offer a more comfortable and adaptable solution to managing their sleep apnea symptoms.12349
Eligibility Criteria
This trial is for adults aged 40-70 with serious mental illnesses like schizophrenia or bipolar disorder, who may also have or be at risk for obstructive sleep apnea. Participants should not have other major psychiatric conditions and must not be under conservatorship.Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a 3-month treatment with an automatic Positive Airway Pressure (PAP) device
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Automatic Positive Airway Pressure (APAP)
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Diego
Lead Sponsor