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Incremental vs Conventional Hemodialysis for Kidney Failure

N/A

Recruiting

Led By David Johnson, Prof

Research Sponsored by The University of Queensland

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Commencing HD as their initial dialysis therapy

Adults (≥ 18 years of age)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 3, 6, 9, 12, 15 and 18 months

Awards & highlights

Study Summary

This trial will test if dialysis is a safe, practical, and cost-effective way to improve quality of life for dialysis patients and families.

Who is the study for?

The INCH-HD trial is for adults over 18 who are starting hemodialysis (HD) as their first treatment for kidney failure. They must be able to consent to the study and likely stay on HD for at least a year. People with urine output less than half a liter per day can't join.Check my eligibility

What is being tested?

This trial compares incremental HD, which gradually increases dialysis frequency, with conventional HD that uses a regular schedule from the start. It aims to see if incremental HD better maintains quality of life and is safe and cost-effective.See study design

What are the potential side effects?

While specific side effects aren't listed here, typical risks associated with hemodialysis may include low blood pressure, muscle cramps, itching, sleep problems, anemia, bone diseases, high blood potassium levels or infection.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am starting hemodialysis as my first dialysis treatment.

Select...

I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 3, 6, 9, 12, 15 and 18 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 3, 6, 9, 12, 15 and 18 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 3, 6, 9, 12, 15 and 18 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Heath related quality of life

Secondary outcome measures

Adverse events and side-effects

Fatigue

Healthcare costs

+13 more

Other outcome measures

Patient lifestyle and wellbeing

Time to event

Trial Design

2Treatment groups

Experimental Treatment

Group I: Incremental HDExperimental Treatment1 Intervention

Participants randomised to incremental HD will commence HD twice weekly and continue until an indication for an increase to three sessions/week (trigger point) is reached.

Group II: Conventional HDExperimental Treatment1 Intervention

Participants randomised to conventional HD will commence HD thrice weekly from the first HD session.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

The University of QueenslandLead Sponsor

140 Previous Clinical Trials

65,844 Total Patients Enrolled

1 Trials studying Kidney Failure

48 Patients Enrolled for Kidney Failure

Medical Research Future FundOTHER

8 Previous Clinical Trials

209,746 Total Patients Enrolled

Queensland HealthOTHER_GOV

4 Previous Clinical Trials

18,516 Total Patients Enrolled

Media Library

Conventional HD Clinical Trial Eligibility Overview. Trial Name: NCT04932148 — N/A

Kidney Failure Research Study Groups: Incremental HD, Conventional HD

Kidney Failure Clinical Trial 2023: Conventional HD Highlights & Side Effects. Trial Name: NCT04932148 — N/A

Conventional HD 2023 Treatment Timeline for Medical Study. Trial Name: NCT04932148 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many centers are responsible for the oversight of this trial?

"Patients are currently being enrolled in 4 separate sites, located in Cleveland, Logan, Woolloongabba and other nearby regions. To reduce the burden of travel for participants, it is recommended that they select a location near to them."

Answered by AI

Is this investigation currently open to new participants?

"Affirmative. According to clinicaltrials.gov, this medical study is currently seeking participants with the first post dated on July 6th 2022 and last updated April 20th 2023. Across four sites, 372 patients need to be recruited for the trial."

Answered by AI

What is the sample size for this clinical investigation?

"Indeed, according to clinicaltrials.gov, the trial is actively pursuing candidates. This research project was published on July 6th 2022 and underwent its latest revision on April 20th 2023. A total of 372 participants will be recruited from 4 separate sites."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

INCremental Dialysis to Improve Health Outcomes in People Starting Haemodialysis (INCH-HD)

2022. "INCremental Dialysis to Improve Health Outcomes in People Starting Haemodialysis (INCH-HD)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04932148.

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