64 Participants Needed

Zypan for Indigestion

AG
RB
Overseen ByRyan Bradley, ND, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: National University of Natural Medicine

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines how a dietary supplement called Zypan affects individuals with functional dyspepsia, a type of indigestion causing upper stomach discomfort. The study aims to determine if Zypan can improve digestion and overall quality of life. Participants will take either Zypan or a placebo (a pill with no active ingredients) for four weeks. Suitable candidates for the trial are adults with ongoing indigestion symptoms but without other chronic stomach issues like ulcers or irritable bowel syndrome (IBS). As an unphased trial, this study allows participants to contribute to understanding how Zypan might benefit those with functional dyspepsia.

Do I have to stop taking my current medications for the trial?

The trial requires that you be on a stable dose of all medications for at least three months before starting. You should not start any new medications or supplements unless advised by a healthcare professional.

Is there any evidence suggesting that Zypan is likely to be safe for humans?

Research has shown that Zypan is generally safe for most people. Many individuals taking Zypan 40mg tablets experience no side effects. Following the recommended dosage is important to minimize risk. For those with liver disease, some sources suggest that Zypan can likely be used safely. Although it is a dietary supplement and not a strong medicine, consulting a doctor before starting any new treatment is always advisable.12345

Why are researchers excited about this trial?

Most treatments for indigestion, like antacids, H2 blockers, and proton pump inhibitors, work by reducing stomach acid. But Zypan is unique because it targets digestive enzymes to improve digestion directly. Researchers are excited about Zypan because it uses a combination of natural enzymes that may enhance the digestive process more effectively than traditional acid-reducing medications. This approach could offer a new way to relieve indigestion symptoms without altering stomach acid levels, potentially reducing side effects.

What evidence suggests that Zypan might be an effective treatment for indigestion?

Research has shown that digestive enzymes, such as those in Zypan, can ease symptoms of functional dyspepsia, a type of indigestion. One study found that taking digestive enzyme supplements improved sleep quality and reduced indigestion symptoms. Another source suggested that Zypan could help 35% of people with acid reflux become symptom-free. This trial will compare Zypan to a placebo to evaluate its effectiveness in improving digestion and overall quality of life for those dealing with functional dyspepsia.14678

Are You a Good Fit for This Trial?

This trial is for adults who frequently experience indigestion, specifically functional dyspepsia. The study aims to see if a dietary supplement can improve their digestion and quality of life.

Inclusion Criteria

I have symptoms like stomach pain or discomfort not related to other diseases.
I am 60 or older and have had a normal stomach scope test.
I haven't taken any antibiotics or drugs for stomach discomfort for the last month.
See 9 more

Exclusion Criteria

I haven't been hospitalized in the last 3 months, except for planned medical procedures not related to stomach issues.
I am currently taking digestive enzyme or betaine HCL supplements.
I have had surgery in my abdomen area, but not for appendicitis.
See 12 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either the dietary supplement or placebo to assess effects on quality of life and digestion

4 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Zypan
Trial Overview The trial is testing the effectiveness of Zypan, a dietary supplement, against a placebo (a pill with no active ingredients). Participants will be randomly assigned to receive either Zypan or the placebo.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Placebo Group
Group I: ZypanExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

National University of Natural Medicine

Lead Sponsor

Trials
34
Recruited
1,400+

Citations

Study Details | NCT06320379 | Zypan Functional DyspepsiaIn a clinical study's protocol, the planned outcome measure that is the most important for evaluating the effect of an intervention/treatment. Most clinical ...
Zypan Functional Dyspepsia | Clinical Research Trial ListingThe purpose of this study is to determine the effects of a readily available dietary supplement on quality of life and digestion in adults ...
3.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/37976892/
Efficacy of digestive enzyme supplementation in functional ...Treatment with digestive enzymes was found to be effective in the reduction of functional dyspepsia symptoms and in the improvement of sleep quality, and is ...
IndigestionAn additional 35% of those suffering with acid reflux could become symptom- free by taking a proper digestive enzyme product like Zypan from Standard Process ...
Dyspepsia (DBCOND0004526)A Study to Evaluate the Efficacy Between Helicobacter Pylori Eradication Therapy and Motilitone in Functional Dyspepsia ... Zypan Functional Dyspepsia, No ...
Zypan Functional Dyspepsia - ClinicalTrials.VeevaThe purpose of this study is to determine the effects of a readily available dietary supplement on quality of life and digestion in adults ...
Zypan 40mg Tablet: View Uses, Side Effects, Price and ...Yes, Zypan 40mg Tablet is relatively safe. Most of the people who take Zypan 40mg Tablet do not get a side effect. It is advised to be taken as ...
Zypan D 10mg/40mg Tablet: Price, Uses, Side Effects & ...Safety Advice for Zypan D 10mg/40mg Tablet in Relation to Liver Patients with liver disease can likely use Zypan D 10mg/40mg Tablet safely.
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