40mg of MitoQ for Multiple Sclerosis

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
VA Portland Health Care System, Portland, OR, Portland, ORMultiple Sclerosis+1 More20 mg MitoQ - Drug
Eligibility
18 - 70
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test if a drug called MitoQ can help reduce fatigue in MS patients.

Eligible Conditions
  • Multiple Sclerosis
  • Fatigue

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 3 Secondary · Reporting Duration: 12 weeks

12 weeks
Beck's Depression Inventory (BDI)
Expanded Disability Status Scale (EDSS)
Modified Fatigue Inventory Scale (MFIS)
Symbol Digit Modalities Test (SDMT)

Trial Safety

Safety Progress

1 of 3

Trial Design

3 Treatment Groups

40mg of MitoQ
1 of 3
20mg of MitoQ
1 of 3
Placebo
1 of 3

Active Control

Non-Treatment Group

60 Total Participants · 3 Treatment Groups

Primary Treatment: 40mg of MitoQ · Has Placebo Group · Phase 1 & 2

40mg of MitoQ
Drug
ActiveComparator Group · 1 Intervention: 40mg of MitoQ · Intervention Types: Drug
20mg of MitoQ
Drug
ActiveComparator Group · 1 Intervention: 20 mg MitoQ · Intervention Types: Drug
Placebo
Drug
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 12 weeks

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,494 Previous Clinical Trials
2,724,254 Total Patients Enrolled
15 Trials studying Multiple Sclerosis
1,138 Patients Enrolled for Multiple Sclerosis
Vijayshree Yadav, MBBSPrincipal InvestigatorVA Portland Health Care System, Portland, OR

Eligibility Criteria

Age 18 - 70 · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have a disability score ranging from mild to severe according to the Expanded Disability Status Scale (EDSS), but are still able to walk.
You have been feeling tired for at least two months and it hasn't gone away.

Who else is applying?

How old are they?
18 - 65100.0%
What site did they apply to?
VA Portland Health Care System, Portland, OR100.0%
What portion of applicants met pre-screening criteria?
Met criteria100.0%

Frequently Asked Questions

Could I be a suitable participant in this experiment?

"To participate in this medical trial, those with multiple sclerosis and aged between 18 to 70 years of age are eligible. A maximum of 60 patients can join the study." - Anonymous Online Contributor

Unverified Answer

Are individuals of all ages being considered for participation in this medical experiment?

"According to the prerequisites of this clinical test, participants must be at least 18 years old and no older than 70." - Anonymous Online Contributor

Unverified Answer

How many individuals have taken part in the research?

"Correct. The information hosted on clinicaltrials.gov asserts that this medical trial, which was originally posted in April 1st 2020, is currently looking for participants to join the study. In total 60 patients will be recruited from one location." - Anonymous Online Contributor

Unverified Answer

Is this research endeavor actively recruiting participants at the moment?

"Affirmative. According to information hosted on clinicaltrials.gov, this investigation is actively seeking volunteers for enrollment. It was first published in April 1st 2020 and has been recently updated on April 15th 2022; with the aim of finding 60 participants from one medical centre." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.