Remote High-Intensity Interval Training for COVID-19 Recovery
(REMM-HIIT-CoV Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment REmotely Monitored, Mhealth supported High Intensity Interval Training for COVID-19 recovery?
Research shows that remote rehabilitation programs, like the COVIDREHAB platform, have been effective in improving lung function and reducing symptoms such as shortness of breath in COVID-19 patients. Additionally, a study on a respiratory telerehabilitation program found it to be effective, safe, and feasible for COVID-19 patients, suggesting that similar remote high-intensity interval training could also be beneficial.12345
Is high-intensity interval training (HIIT) safe for humans?
How is the REMM-HIIT-CoV treatment different from other COVID-19 recovery treatments?
The REMM-HIIT-CoV treatment is unique because it combines high-intensity interval training (HIIT) with remote monitoring and mobile health support, allowing patients to engage in a structured rehabilitation program from home. This approach is particularly beneficial for those who cannot access in-person rehabilitation services, offering a novel way to improve recovery and lung function after COVID-19.12479
What is the purpose of this trial?
Multicenter, prospective, randomized controlled trial providing mobile health supported physical rehabilitation to 120 patients who have been critically ill with COVID-19 and who complete at least one exercise session.
Research Team
Paul Wischmeyer, MD
Principal Investigator
Duke Clinical Research Institute
Eligibility Criteria
This trial is for adults over 18 who were hospitalized with COVID-19 and can walk on their own or with a cane. They should be going home directly from the hospital, not to another care facility, and must be able to exercise and use an iPhone for mobile health coaching.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a remotely monitored, mobile health-supported high intensity interval rehabilitation exercise training program
Follow-up
Participants are monitored for changes in physical function, cognitive ability, muscle mass, and other health metrics
Extended Follow-up
Participants are monitored for long-term changes in health metrics such as EQ-5D-5L Score, Lawton Score, and biomarkers of aging and inflammation
Treatment Details
Interventions
- REmotely Monitored, Mhealth supported High Intensity Interval Training
- REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program with High Intensity Interval Training
REmotely Monitored, Mhealth supported High Intensity Interval Training is already approved in United States for the following indications:
- Rehabilitation after COVID-19 critical illness
Find a Clinic Near You
Who Is Running the Clinical Trial?
Duke University
Lead Sponsor
Florida Atlantic University
Collaborator
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborator
Vanderbilt University Medical Center
Collaborator
Ohio State University
Collaborator
University of Kentucky
Collaborator
University of Alabama at Birmingham
Collaborator