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Rapamycin for Aging (mTOR Trial)
mTOR Trial Summary
This trial will test whether rapamycin can improve the health of elderly humans by looking at various age-related declines. One part of the trial will focus on cardiac function.
mTOR Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowmTOR Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2022 Phase 2 & 3 trial • 107 Patients • NCT03826628mTOR Trial Design
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Who is running the clinical trial?
Media Library
- I am a female interested in participating in a clinical trial.I have been on long-term immunosuppressants like prednisone in the past year.You need to be in good overall health, which means you should feel physically and mentally well, and have a good social life.I had a heart attack or active heart disease in the last 6 months.I have had skin ulcers or issues with wounds not healing well.I have a liver condition.My chronic conditions, like high blood pressure or heart disease, are under control.I have diabetes with an A1c level of 6.5 or higher, or I am on medication for it.I am not taking medications like diltiazem or erythromycin that affect drug metabolism.You are a smoker.I am taking Coumadin for blood thinning.I am between 70 and 95 years old.My health conditions are stable, with or without medication.I have had an intestinal disorder in the last 6 months.
- Group 1: Rapamycin
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How is rapamycin most commonly used?
"Rapamycin can be used to treat patients that have been rejected from a liver or kidney transplant as well as those suffering from certain diseases."
Are there any positions available in this clinical trial for new patients?
"This study, which was originally posted on February 1st, 2022, is currently looking for participants. The most recent update to the listing was on May 17th, 2022."
What other drugs has rapamycin been tested against in previous clinical trials?
"There are presently 130 trials ongoing that rapamycin is being studied in. Of these, 13 are large-scale Phase 3 studies. Most of the research for rapamycin is centred in Cincinnati, Ohio; though, there are 1084 locations running clinical trials involving rapamycin."
Has the FDA accepted rapamycin for therapeutic use?
"While there is some evidence that rapamycin is safe, it has not yet been proven effective in clinical trials. Therefore, it receives a score of 2."
How many people are enrolled in this experiment?
"Per the information provided on clinicaltrials.gov, this study is still recruiting patients. The trial was originally posted on February 1st, 2022 and was most recently edited on May 17th, 2022. The trial is looking for 12 participants that will be seen at 2 locations."
Who would this clinical trial be appropriate for?
"The study is currently seeking 12 individuals aged 70-95 that meet the following health requirements: good general health, clinically stable chronic diseases, and complete physical, mental, and social well-being."
Could older patients benefit from this treatment option?
"The oldest patients that can be recruited for this study are 95 years old, and the youngest patients must be at least 70."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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