This trial is evaluating whether NMES will improve 1 primary outcome and 4 secondary outcomes in patients with Wounds. Measurement will happen over the course of 0 and 9 months.
This trial requires 20 total participants across 2 different treatment groups
This trial involves 2 different treatments. NMES is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are in Phase 2 & 3 and have had some early promising results.
"The signs of spinal cord injuries include paralysis of all limbs on one side of the body, loss of bowel and bladder control, and bladder or bowel incontinence. Some other signs may include loss of sensation and urinary incontinence." - Anonymous Online Contributor
"Despite advances in the field of SCI care, a small but meaningful number of patients survive long-term disability. Survival is strongly associated with completeness of injury, and is higher in younger patients, and in patients with full mobility and good functioning, with or without the use of assistive devices." - Anonymous Online Contributor
"There is no clear cause for spinal cord injuries. A number of factors in the setting of the injury may result in injury, but the mechanism is not known. It is thought that genetic factors predispose to spinal cord injury, resulting in a defect in the central processing of neural signals, leading to a failure in motor and communication between the brain and the body, and to an inability to move. However, other factors, such as injuries, drug use, and malnutrition, have been found to cause serious injuries and complicate treatment. There is no clear cause for these conditions, although they might occur concurrently, or be caused by an underlying genetic predisposition. It is estimated that 10% of individuals with SCI develop chronic pain." - Anonymous Online Contributor
"A [spinal cord injury](https://www.withpower.com/clinical-trials/spinal-cord-injury) is not treatable by one treatment, but is treatable with many different therapeutic modalities. A variety of medications are commonly prescribed to patients who have sustained spinal cord injuries, and some medications have been shown to have a significant impact on recovery. However, no treatment has been proven to be a 'wins' all treatment – patients still require multiple treatments to achieve the best possible results. Treatment for a spinal cord injury can be divided into functional and psychosocial categories. Functional treatment is focused on minimizing muscle pain, preventing bed sores and bladder control issues. Functional therapy may also include strengthening the patient's muscles, decreasing stress that is caused by their injuries and helping them regain control of their bladder and bowel habit." - Anonymous Online Contributor
"Approximately 19,000 people get a SCI in the United States each year. This is an estimate since it is difficult to define what constitutes a spinal cord injury. Even if the number of people in the United States sustaining SCI remained constant and no preventive interventions were implemented, it is estimated that approximately 1,400 would still be injured annually. SCI and the associated costs continue to grow as the patient population continues to expand." - Anonymous Online Contributor
"This classification would classify SCIs in a very logical way. This classification can be a first step in the process that will eventually lead to an improvement of clinical management and research. A classification scheme will undoubtedly be the ultimate goal to accomplish in the future." - Anonymous Online Contributor
"A common concern about Nmes is potential neurological toxicity. There was moderate to moderate evidence that there is no additive or synergistic effect with Nmes following other treatments. There was moderate to moderate evidence of no synergistic or additive effect with dexamethasone. This is in keeping with the FDA label statement which states that if used in conjunction with another known treatment or medication, the use of DEX + NME should be considered a precaution. However, the FDA will not allow use of NME in conjunction with NESTIN. There was limited evidence that there is a significant decrease in urinary or renal toxicity when compared with the same amount used in combination of placebo." - Anonymous Online Contributor
"Results from a recent paper has found only a small number of SCI cases reported to the ABI of SCI registry, with no significant differences between countries. It appears that SCI families tend to be relatively small and the genetic factors associated with SCI is likely to be complex and rare." - Anonymous Online Contributor
"Results from a recent clinical trial indicate that NMES reduces upper extremity muscle strength in the majority of cases. To confirm a non-pain a positive outcome result from both an intracortical EMG and a transcranial direct current stimulation (tDCS) of the motor cortex. Prospective studies are needed to determine the long term effects of nmes treatment for the treatment of upper extremity muscle wasting secondary to a spinal cord injury." - Anonymous Online Contributor
"Results from a recent paper presented herein are the first to demonstrate that NMes is significantly more effective at reducing pain than a placebo in the acute phase of stroke rehabilitation. A larger study in the subacute and chronic phases of stroke rehabilitation is required." - Anonymous Online Contributor
"Recent findings, patients with spinal cord injuries (SCI) reported a marked improvement in their quality of life after their injury (QOLI-SCI), and a marked improvement was seen in patients with nmes after their injury. Recent findings can be further used to develop more comprehensive guidelines that can be used by clinicians who manage SCI patients with nmes." - Anonymous Online Contributor
"Nmes is a risk tool that carries a serious risk and only should be recommended in those with a history of falls or significant mobility difficulties. Findings from a recent study show that fallers are at particular hazard and this should be taken into account in the decision making on nmes use." - Anonymous Online Contributor