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Arm A for Melanoma

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Dana Farber Cancer Institute, Boston, MAMelanomaInvestigators Choice - Drug
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial evaluates if a new drug is better than current treatments for advanced melanoma.

Eligible Conditions
  • Advanced Melanoma

Treatment Effectiveness

Effectiveness Progress

1 of 3

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Pembrolizumab Injection [Keytruda]
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Treatment Arm

Study Objectives

1 Primary · 5 Secondary · Reporting Duration: from first dose to approximately 2 years

Year 2
Phase 2 Secondary
Safety: Adverse Events and Severe Adverse Events
Safety: Tolerability
Serum Pharmacokinetics
Week 3
Efficacy: Disease Control Rate
Year 2
Phase 2 Primary

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Similar Trials

1
APX005M
1
Pembrolizumab Injection [Keytruda]
1
Treatment Arm

Trial Design

3 Treatment Groups

Arm A
1 of 3
Arm B
1 of 3
Arm C
1 of 3

Experimental Treatment

460 Total Participants · 3 Treatment Groups

Primary Treatment: Arm A · No Placebo Group · Phase 2 & 3

Arm A
Drug
Experimental Group · 1 Intervention: Tebentafusp · Intervention Types: Drug
Arm B
Drug
Experimental Group · 1 Intervention: Tebentafusp with Pembrolizumab · Intervention Types: Drug
Arm C
Drug
Experimental Group · 1 Intervention: Investigators Choice · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: from first dose to approximately 2 years

Who is running the clinical trial?

Immunocore LtdLead Sponsor
10 Previous Clinical Trials
2,116 Total Patients Enrolled
7 Trials studying Melanoma
1,773 Patients Enrolled for Melanoma
Mohammed Dar, MDStudy DirectorImmunocore Ltd
3 Previous Clinical Trials
834 Total Patients Enrolled
2 Trials studying Melanoma
690 Patients Enrolled for Melanoma

Eligibility Criteria

Age 18+ · All Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have advanced melanoma that cannot be removed by surgery.
References

Frequently Asked Questions

Are there still available spots in this exploration of treatments?

"As published on clinicaltrials.gov, this research is actively searching for suitable candidates. The trial was posted in December of 2022 and the information has been updated as recently as February 2021." - Anonymous Online Contributor

Unverified Answer

What is the scope of recruitment for this research endeavor?

"Affirmative. The research posted on clinicaltrials.gov reveals that this medical trial is actively looking for applicants, with the initial posting being on December 19th 2022 and an update occurring as recently as February 21st 2023. 460 participants must be enrolled from 2 different sites." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

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