Emanate Perio PODS for Severe Gum Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether a new periodontal hydrogel dressing, Emanate Perio PODS, enhances healing in severe gum disease better than no treatment after deep cleaning. Participants will be divided into groups: one will use the gel overnight, another will use it twice a day, and a control group will receive no additional treatment. The trial aims to determine if the gel improves healing in individuals with severe gum disease after cleaning. Ideal participants have experienced severe gum disease with deep gum pockets for at least a year and are willing to avoid certain dental products during the study. As an unphased trial, this study allows participants to contribute to innovative dental research that could improve future treatments.
Will I have to stop taking my current medications?
You may need to stop taking certain medications before joining the trial. Specifically, you cannot take medications that affect gum conditions, regular antibiotics, corticosteroids, or certain pain and blood-thinning medications. It's best to discuss your current medications with the trial team to see if any changes are needed.
What prior data suggests that Emanate Perio PODS is safe for treating severe gum disease?
Research has shown that treatments using chlorhexidine, such as Emanate Perio PODS, are generally safe for treating gum disease. Chlorhexidine, a common ingredient, helps reduce bacteria in the mouth. Many studies have found it to be well-tolerated by patients. Although detailed information specifically about Emanate Perio PODS is limited, these findings suggest it could be safe for individuals with severe gum disease. It is always important to consult a healthcare provider about any concerns before joining a trial.12345
Why are researchers excited about this trial?
Unlike the standard treatments for severe gum disease, which often involve antibiotics and more invasive procedures, Emanate Perio PODS represent a novel approach by employing a localized delivery method. This treatment is unique because it's designed to target the affected area directly, potentially enhancing effectiveness while minimizing systemic side effects. Researchers are particularly excited about the convenience and potential for rapid results, as one group uses the PODS overnight while another applies them twice a day for just 30 minutes. This innovative strategy could offer a more patient-friendly and efficient way to manage severe gum disease.
What evidence suggests that Emanate Perio PODS is effective for severe gum disease?
Research has shown that treatments like Emanate Perio PODS, similar to ozone therapy, can help treat gum disease by promoting healing and fighting infections. Studies suggest these therapies improve wound healing after plaque and tartar removal from teeth. In this trial, participants will join different groups to test the effectiveness of Emanate Perio PODS. Group A will use the PODS overnight for 14 days post-SRP, while Group B will use them twice a day for 30 minutes over the same period. Group C will serve as a control with no treatment post-SRP. Emanate Perio PODS use a special gel to enhance the healing process. Early results from similar treatments have shown promise in improving gum health and reducing severe gum disease symptoms. Overall, this approach is expected to help people with periodontitis recover faster and achieve better results.12678
Who Is on the Research Team?
Jarret Fass
Principal Investigator
Emanate Biomedical
Are You a Good Fit for This Trial?
This trial is for people with generalized stage III periodontitis, a severe form of gum disease. Participants must have had plaque and tartar removed from their teeth recently. Specific inclusion or exclusion criteria are not provided, but typically participants should be in stable health and meet certain age requirements.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive Emanate Perio PODS dressing post-SRP for 14 days, either overnight or 2x/day for 30 minutes
Follow-up
Participants are monitored for safety and effectiveness after treatment, with primary outcome measures assessed at 60 days post non-surgical therapy
What Are the Treatments Tested in This Trial?
Interventions
- Emanate Perio PODS
Find a Clinic Near You
Who Is Running the Clinical Trial?
McGuire Institute
Lead Sponsor
Emanate Biomedical Inc.
Industry Sponsor