Acupuncture, Anesthetic Spray, or Masking Tape for Gagging

DP
Overseen ByDevon Ptak
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests three methods to reduce the gag reflex: acupuncture, anesthetic spray (a numbing agent), and masking tape. The goal is to assess how each method affects the gag response when triggered. It is ideal for individuals who frequently experience gagging, particularly during dental visits, and have a strong gag reflex when a swab touches the back of the mouth. Participants should belong to the Tufts dental community and have a noticeable gag reflex. As an Early Phase 1 trial, this research aims to understand how these methods work in people, offering participants a chance to contribute to pioneering solutions for managing gag reflexes.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but if you are using anticoagulants (blood thinners), you cannot participate.

What prior data suggests that these techniques are safe for reducing gag reflex?

Research has shown that acupuncture, particularly at a point called CV-24, can safely and effectively manage the gag reflex. This quick and non-invasive method takes just a few minutes, and studies indicate that most people tolerate it well.

In contrast, anesthetic sprays, often containing benzocaine, present some safety concerns. Benzocaine can rarely cause methemoglobinemia, a serious condition affecting how blood carries oxygen. Ensuring no allergy to benzocaine or similar substances is crucial.

Using masking tape is a simple and non-invasive method to help manage the gag reflex by acting as a physical barrier, and no significant safety issues have been reported with its use.

Each treatment has its own safety considerations, so weighing options or consulting a healthcare provider is important.12345

Why are researchers excited about this trial's treatments?

Researchers are excited about these treatments for gag reflex management because they offer non-traditional, innovative approaches that could provide new options for patients. Unlike standard methods like desensitizing agents or behavioral techniques, acupuncture at the mentolabial fold (CV-24) uses a novel application technique with an endodontic file, which may offer a unique reflex modulation. The anesthetic spray provides a quick, direct application to the throat, potentially offering fast-acting relief. Meanwhile, applying masking tape to the mentolabial fold is an unexplored method that might offer a simple mechanical solution to reducing gag reflex. These diverse strategies could revolutionize gag management by offering alternatives that are potentially quicker or more accessible than current treatments.

What evidence suggests that this trial's treatments could be effective for reducing gag reflex?

This trial will compare the effectiveness of acupuncture, anesthetic spray, and masking tape in reducing the gag reflex. Research has shown that acupuncture at a specific point, called CV-24, can quickly reduce the gag reflex during medical procedures. Participants in this trial may receive acupuncture as one of the treatment options. Anesthetic sprays, another treatment option, have proven effective, as evidence indicates they greatly reduce gagging compared to not using them. Specifically, one study found that people who used an anesthetic spray had a much lower gag reflex than those who did not. As for masking tape, the third treatment option, specific data on its effectiveness in reducing the gag reflex is limited, but it is being explored as a possible method.12678

Who Is on the Research Team?

DP

Devon Ptak

Principal Investigator

Tufts University School of Dental Medicine

Are You a Good Fit for This Trial?

This trial is for individuals aged 18 or older who are part of Tufts SDM and have a strong gag reflex, scoring at least a 2 on the Gagging Severity Index. Participants must react to cotton swab stimulation in their mouth. Pregnant women, those allergic to xylocaine, using anticoagulants, with bleeding disorders, or unable to consent due to cognitive impairment cannot join.

Inclusion Criteria

Students, faculty, or staff of Tufts SDM
Subjects who score a 2 or higher on the Gagging Severity Index (GSI) and have a positive gag reflex response when stimulated with a cotton swab at the base of the tongue/uvula/tonsil region
I am 18 years old or older.

Exclusion Criteria

Allergy to xylocaine
Those who participated in the Calibration phase of this study
Wards of the state
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

Intervention

Participants receive one of the interventions: acupuncture, tape, or anesthetic spray, to evaluate reduction in gag reflex

90 minutes
1 visit (in-person)

Follow-up

Participants are monitored for immediate effects of the intervention on gag reflex severity

Immediately post-intervention

What Are the Treatments Tested in This Trial?

Interventions

  • Acupuncture
  • Anesthetic spray
  • Masking Tape
Trial Overview The study tests three methods to reduce severe gag reflex: acupuncture at point CV-24, applying masking tape across certain areas of the face believed by some cultures to help with gagging, and anesthetic spray. The main goal is seeing which method best reduces the gag reflex after it's triggered.
How Is the Trial Designed?
3Treatment groups
Experimental Treatment
Group I: TapeExperimental Treatment1 Intervention
Group II: Anesthetic sprayExperimental Treatment1 Intervention
Group III: Acupuncture (CV-24)Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Tufts University

Lead Sponsor

Trials
271
Recruited
595,000+

Citations

Acupuncture for Relief of Gag Reflex in Patients ...The needling of acupuncture point CV24 was described to be effective in reducing the gag reflex during TEE in patients with ischemic stroke or transient ...
Acupuncture for gag reflex during upper alginate impressionAcupuncture has a nearly instant effect in controlling the gag reflex in eight out of ten patients. Acupuncture can reduce the discomfort for ...
Effective Interventions to Overcome Severe Gag ReflexFollowing randomization to one of three interventions ( acupuncture , anesthetic spray, or masking tape), GSI will be recorded again. The change in GSI score ...
Laser Acupuncture for Gag Reflex & Dental Impressions TrialThis study found that the application of laser acupuncture on PC6 and CV24 acupuncture points might be effective in reducing the gag reflex and can be used as ...
5.pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov/17159959/
Acupuncture controlling gag reflex in patients: an auditConclusion: Our results indicate that acupuncture of point CV-24 is an effective method of controlling severe GR during dental treatment ...
Exploring alternative methods of gag reflex control Part 2Acupuncture has been described as quick (2-3 minutes of appointment time), non-invasive, safe and cost effective with a material price of £0.20 ...
Gag Reflex Control through Acupuncture: A Case SeriesThe aim of the present study therefore was to evaluate whether acupuncture can produce a reduction of the gag reflex. Methods. A total of 20 patients, aged ...
Evaluating Efficacy of P-6 vs. CV-24 Acupressure Points in ...The study aims at evaluation and comparison of the efficacy of using acupressure points CV-24 and P-6 in controlling the severity of gag reflex.
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