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Ketamine for Electroconvulsive Therapy

Phase < 1
Waitlist Available
Research Sponsored by University of New Mexico
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up this will be assessed throughout the year.
Awards & highlights

Study Summary

The investigators will be examining slow-wave characteristics in depressed patients receiving electroconvulsive therapy (ECT) using direct current electroencephalogram (dcEEG) by anesthesia induction agent.

Eligible Conditions
  • Electroconvulsive Therapy
  • Electroencephalogram
  • Ketamine
  • Major Depressive Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~this will be assessed throughout the year.
This trial's timeline: 3 weeks for screening, Varies for treatment, and this will be assessed throughout the year. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Clinical Efficacy of ECT
Secondary outcome measures
Cognitive performance
Direct current electroencephalogram slow wave phenomenon (exploratory outcome)
ECT parameters and their correlation to production of slow-wave phenomenon

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: KetamineExperimental Treatment1 Intervention
Standard of care anesthesia that suppresses slow wave characteristics
Group II: MethohexitalActive Control1 Intervention
Standard of care anesthesia that does not affect slow wave characteristics
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ketamine
2011
Completed Phase 4
~1120

Find a Location

Who is running the clinical trial?

University of New MexicoLead Sponsor
376 Previous Clinical Trials
3,528,691 Total Patients Enrolled
~2 spots leftby Jun 2025