Dual Task Training for Mild Cognitive Impairment
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores a new approach to help older adults with mild cognitive impairment (MCI) improve balance and reduce fall risk. The study focuses on "dual task perturbation training," which combines cognitive exercises (such as memory and reaction games) with physical balance training on a motorized treadmill. Participants face balance challenges while performing mental tasks to determine if this method enhances stability and cognitive function. Suitable candidates for this trial are those over 55 with mild cognitive impairment who can walk 10 meters without assistance. As an unphased trial, it offers participants the chance to contribute to innovative research that could enhance balance and cognitive function in older adults.
Will I have to stop taking my current medications?
The trial does not specify whether you need to stop taking your current medications, but you cannot participate if you are on sedative drugs.
What prior data suggests that this dual task perturbation training is safe for older adults with mild cognitive impairment?
Studies have shown that dual task perturbation training helps older adults with mild cognitive impairment (MCI) improve balance and reduce the risk of falls. This method combines mental exercises, such as memory games, with physical activities to enhance both brain and body function.
Research indicates that older adults with MCI find tasks requiring both thinking and moving more challenging. However, this training is generally well-tolerated, with no significant reports of serious side effects. Previous findings suggest that this type of training can improve balance and physical responses without causing harm.
This study does not involve traditional medications but focuses on exercises that might help prevent falls. This intervention is considered safe for most participants, as it mainly involves familiar activities like walking, with added mental challenges to engage the mind.12345Why are researchers excited about this trial?
Researchers are excited about dual task perturbation training for mild cognitive impairment because it combines physical and cognitive exercises in a novel way. Unlike traditional treatments that may focus solely on cognitive exercises or physical therapy, this approach integrates both simultaneously, potentially enhancing the brain’s ability to manage multiple tasks. This method aims to improve working memory, executive functioning, and other cognitive skills while also helping with balance and coordination. By challenging the brain and body together, researchers hope to see more significant improvements in cognitive function and daily living skills than with standard care options.
What evidence suggests that this trial's dual task perturbation training could be effective for mild cognitive impairment?
Research has shown that older adults with mild cognitive impairment (OAwMCI) often struggle with balance and movement, particularly when performing dual tasks like thinking and walking. Studies indicate they face challenges with both tasks, increasing their risk of falling. In this trial, participants will engage in dual task training, which combines thinking exercises with balance challenges. Previous studies have demonstrated that this training helps them manage balance disturbances, reduce falls, and improve balance maintenance. These findings suggest that dual task training could effectively enhance balance and reduce fall risks in OAwMCI.12356
Who Is on the Research Team?
Tanvi Bhatt
Principal Investigator
University of Illinois at Chicago
Are You a Good Fit for This Trial?
This trial is for older adults over 55 with mild cognitive impairment (MOCA score <26). Participants must be able to walk unassisted for more than 10 meters, not use sedatives, have no recent major surgeries or hospitalizations, and can't have chronic neurological, cardiopulmonary, musculoskeletal diseases. They should understand English and meet certain heart rate and blood pressure criteria.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Single Session Training
Participants receive a single session of dual-task perturbation training to familiarize with cognitive tasks and undergo perturbation trials.
Multiple Session Training
Participants undergo 4 weeks of dual-task perturbation training involving cognitive and motor tasks to improve balance and cognitive function.
Follow-up
Participants are monitored for retention of improvements in stability control, cognition, and fall reduction for at least 3 months post-training.
What Are the Treatments Tested in This Trial?
Interventions
- Dual task perturbation training
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Illinois at Chicago
Lead Sponsor
National Institute on Aging (NIA)
Collaborator
Roybal Predoctoral pilot grant
Collaborator