Brain Scans for Cognitive Functioning
(fMRI Pilots Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to understand the activity of certain brain areas while military pilots perform flight simulations. Researchers use functional magnetic resonance imaging (fMRI) to identify which brain parts engage during these virtual reality exercises. The goal is to observe how brain activity changes over time with training. Active duty military pilots, either in instructor or remote piloted aircraft training, qualify if they haven't experienced serious head injuries, frequent migraines, or certain neurological conditions. As an unphased study, this trial offers a unique opportunity to contribute to groundbreaking research on brain activity in pilots.
Will I have to stop taking my current medications?
The trial information does not specify if you need to stop taking your current medications. However, if you have a history of migraines requiring frequent medication, you may not be eligible to participate.
What prior data suggests that this fMRI with virtual reality flight simulator is safe?
Research has shown that using fMRI (a type of brain scan) with a virtual reality flight simulator is generally safe. Many studies have explored this combination for training purposes, aiming to understand how the brain functions during tasks requiring focus and precision, such as flying a plane.
These studies have not reported any major safety issues. Most participants handle the technology well, typically experiencing no negative side effects from the brain scans or virtual reality simulations.
Since fMRI commonly examines brain activity and virtual reality is often used for training, both are considered safe in these settings. Overall, for those considering joining a trial using these methods, evidence suggests it is quite safe.12345Why are researchers excited about this trial?
Researchers are excited about using fMRI combined with a virtual reality flight simulator to study cognitive functioning because it offers a fresh approach to understanding brain activity in real-time. Unlike traditional cognitive assessments that rely on paper-based tests or simple computer tasks, this method provides a dynamic and immersive experience, allowing scientists to observe how different parts of the brain engage during complex tasks similar to real-world scenarios. Additionally, the use of fMRI imaging allows for detailed insights into both functional and anatomical changes in the brain over time, potentially leading to breakthroughs in diagnosing and monitoring cognitive disorders.
What evidence suggests that fMRI with virtual reality flight simulator is effective for identifying cognitive circuits in military aviators?
Research shows that using virtual reality (VR) with brain scans can aid in studying brain function during complex tasks. For example, new evidence suggests that VR enhances understanding of movement and movement awareness. Training in a VR setting has also boosted mental skills like visuospatial ability, which involves how the brain perceives and remembers spatial locations. In this trial, participants will undergo fMRI with a virtual reality flight simulator to observe brain activity during tasks such as flying. Early studies suggest that this approach may reduce mental fatigue affecting performance. These findings indicate that this technology could be useful for studying and potentially improving mental performance in certain situations.12678
Who Is on the Research Team?
Paul Sherman, MD
Principal Investigator
59th Medical Wing Science and Technology
Are You a Good Fit for This Trial?
This trial is for individuals who are being trained in military aviation and will participate in a study involving virtual reality flight simulation. The key requirement is that they must be available for brain scans at two different times during their training.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Initial Imaging and Simulation
Initial anatomic imaging and fMRI with virtual reality flight simulator scan
Repeat Imaging and Simulation
Repeat testing performed at approximately 2 months after initial scan
Follow-up
Participants are monitored for changes in brain activity and anatomy over time
What Are the Treatments Tested in This Trial?
Interventions
- fMRI with virtual reality flight simulator
Find a Clinic Near You
Who Is Running the Clinical Trial?
The Geneva Foundation
Lead Sponsor
59th Medical Wing
Collaborator
Uniformed Services University of the Health Sciences
Collaborator