Visudyne

Pathologic myopia, Histoplasmosis retinitis, Macular Degeneration + 1 more

Treatment

18 Active Studies for Visudyne

Treatment for

Pathologic myopia

What is Visudyne

VerteporfinThe Generic name of this drug

Treatment SummaryVerteporfin, also known by the brand name Visudyne, is a drug used to treat wet form macular degeneration. The drug is administered and then triggered by nonthermal red light with a wavelength of 693 nm in the presence of oxygen. The light and oxygen activate the drug creating highly reactive substances which damage the blood vessels in the affected area. This blocks the vessels and eliminates abnormal blood vessels.

Visudyneis the brand name

image of different drug pills on a surface

Visudyne Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Visudyne

Verteporfin

2000

Effectiveness

How Visudyne Affects PatientsVerteporfin, also known as benzoporphyrin derivative, is a medication used with laser treatment to reduce abnormal blood vessels in the eye caused by certain conditions, such as wet macular degeneration. When exposed to red light at a certain wavelength (693 nm) and oxygen, it reacts and produces oxygen radicals that damage the blood vessels and block them.

How Visudyne works in the bodyVerteporfin is spread throughout the body when taken. When activated by light, it creates oxygen molecules that can damage cells. This damage can be used to close off blood vessels in the eye, and form clots. It can also be used to kill tumor cells, because the oxygen molecules it creates are toxic. Verteporfin seems to collect more in newly-formed blood vessels and in the retina.

When to interrupt dosage

The dose of Visudyne relies on the diagnosed situation, including Age-Related Macular Degeneration, Histoplasmosis retinitis and Pathologic myopia. The measure of dosage is contingent upon the approach of delivery recorded in the table beneath.

Condition

Dosage

Administration

Pathologic myopia

, 15.0 mg, 2.0 mg/mL

, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous

Histoplasmosis retinitis

, 15.0 mg, 2.0 mg/mL

Macular Degeneration

, 15.0 mg, 2.0 mg/mL

Age-Related Macular Degeneration

, 15.0 mg, 2.0 mg/mL

Warnings

Visudyne Contraindications

Condition

Risk Level

Notes

Porphyrias

Do Not Combine

There are 2 known major drug interactions with Visudyne.

Common Visudyne Drug Interactions

Drug Name

Risk Level

Description

Porfimer sodium

Minor

Verteporfin may increase the photosensitizing activities of Porfimer sodium.

Padeliporfin

Moderate

Verteporfin may increase the photosensitizing activities of Padeliporfin.

Visudyne Toxicity & Overdose RiskTaking too much of this drug or exposing the treated eye to too much light may lead to a lack of oxygen in the normal retinal vessels, which can cause a significant decrease in vision that could be permanent. An overdose of the drug may also increase the amount of time a patient is sensitive to bright light.

image of a doctor in a lab doing drug, clinical research

Visudyne Novel Uses: Which Conditions Have a Clinical Trial Featuring Visudyne?

17 active investigations are assessing the potential of Visudyne to address Histoplasmosis retinitis, Pathologic myopia and Age-Related Macular Degeneration.

Condition

Clinical Trials

Trial Phases

Macular Degeneration

0 Actively Recruiting

Histoplasmosis retinitis

0 Actively Recruiting

Pathologic myopia

0 Actively Recruiting

Age-Related Macular Degeneration

18 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Phase 3, Early Phase 1

Visudyne Reviews: What are patients saying about Visudyne?

2.7Patient Review

7/21/2008

Visudyne for Histoplasmosis Fungus Disease of the Eye

I had a PDT with Visudyne and an Avastin shot. I lost my sight for five minutes, which was scary, but I felt that the two drugs together worked better than in the past. I was in pain for two days, but I felt like I recovered faster than after my previous treatments.

1.7Patient Review

6/18/2011

Visudyne for Formation of New Blood Vessels in the Choroid of the Eye

Do not use this for eye problems. The after effects have been as if I am poisened.No improvement to my sight but vomiting, nausea, joint pains & stiffness,nervous disorder & trembling in left arm. General feeling of unspecified neurological disturbance at 5 weeks after photo dynamic therapy with Visudyne injection.

1Patient Review

9/13/2011

Visudyne for Age-Related Wet Macular Degeneration

My vision actually worsened after using this treatment for wet macular degeneration.

Patient Q&A Section about visudyne

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Visudyne available in USA?

"At this time, there is no Visudyne equivalent available in the US. This means that it is not possible to get the same exact medication from another source. There are fraudulent online pharmacies which may claim to sell a generic version of Visudyne, but this would be illegal."

Answered by AI

What company makes Visudyne?

"Bausch + Lomb strives to provide patients with the best possible treatments for retinal conditions. Our three primary treatments are: Xipere, Visudyne, and Retisert. Xipere is a retinal prosthesis that helps patients to see better. Visudyne is an anti-angiogenic drug that helps to prevent the growth of new blood vessels in the retina. Retisert is a silicone implant that helps to release a continuous stream of medication directly to the back of the eye."

Answered by AI

What is Visudyne used for?

"Verteporfin for injection is used along with laser light treatment to stop leaking from blood vessels in the eye due to the following serious eye conditions: age-related macular degeneration, pathologic myopia, or choroidal neovascularization."

Answered by AI

How much is Visudyne cost?

"A brief guide to the cost of Visudyne: one powder for injection costs approximately $1,800."

Answered by AI

Clinical Trials for Visudyne

Have you considered Visudyne clinical trials? We made a collection of clinical trials featuring Visudyne, we think they might fit your search criteria.

Have you considered Visudyne clinical trials? We made a collection of clinical trials featuring Visudyne, we think they might fit your search criteria.