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What is Tetracaine Hydrochloride
TetracaineThe Generic name of this drug
Treatment SummaryTetracaine is an anesthetic that comes in the form of a cream or patch and is used in combination with lidocaine to numb the skin and reduce pain.
Cetacaine Anestheticis the brand name
Tetracaine Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cetacaine Anesthetic
Tetracaine
1958
21
Effectiveness
How Tetracaine Hydrochloride works in the bodyTetracaine numbs the area it is applied to by blocking sodium channels in the nerves, which prevents them from sending signals.
When to interrupt dosage
The measure of Tetracaine Hydrochloride is contingent upon the diagnosed condition, including Sunburn, Insect Bites and Dermabrasion. The amount likewise fluctuates depending on the delivery procedure (e.g. Spray - Topical or Cream - Topical) featured in the table beneath.Condition
Dosage
Administration
Sunburn
0.07 mg/mg, , 10.0 mg/mL, 0.04 mg/mg, 5.0 mg/mL, 70.0 mg, 0.02 mg/mg, 20.0 mg/mL, 25.0 mg/mL, 2.4 mg/mL, 2.0 %, 0.5 %, 20.0 mg, 7.0 %, 1.0 %, 30.0 mg/mL, 0.02 mg/mL, 0.0066 mg/hour, 0.1 mg/mg, 0.01 mg/mg, 2.0 mg/mL, 1.0 mg/mL, 2.0 mg/pump actuation, 0.0116 mg/mg, 0.0754 mg/mg
, Topical, Cream, Cream - Topical, Subarachnoid, Injection, powder, for solution, Injection, powder, for solution - Subarachnoid, Aerosol, spray, Aerosol, spray - Topical, Injection, Injection - Subarachnoid, Ophthalmic, Solution, Solution - Ophthalmic, Cutaneous, Patch, Patch - Cutaneous, Liquid, Liquid - Ophthalmic, Dental; Topical, Gel, Gel - Dental; Topical, Dental, Gel - Dental, Spray, Spray - Topical, Gel - Topical, Buccal, Gel - Buccal, Intraspinal, Powder, for solution, Powder, for solution - Intraspinal, Oral; Topical, Gel - Oral; Topical, Aerosol, metered, Aerosol, metered - Oral; Topical, Solution / drops, Solution / drops - Ophthalmic, Aerosol, metered - Topical, Aerosol, metered - Dental, Oral, Aerosol, Aerosol - Oral, Liquid - Topical, Solution - Topical, Ointment, Ointment - Topical, Aerosol - Topical, Nasal, Spray - Nasal, Patch - Topical, Infiltration; Subcutaneous; Topical, Liquid - Infiltration; Subcutaneous; Topical, Infiltration; Subcutaneous, Liquid - Infiltration; Subcutaneous, Infiltration, Liquid - Infiltration, Infiltration; Topical, Kit, Kit - Infiltration; Topical, Parenteral; Topical, Liquid - Parenteral; Topical, Injection - Oral, Lotion - Topical, Lotion
Haemorrhoids
0.07 mg/mg, , 10.0 mg/mL, 0.04 mg/mg, 5.0 mg/mL, 70.0 mg, 0.02 mg/mg, 20.0 mg/mL, 25.0 mg/mL, 2.4 mg/mL, 2.0 %, 0.5 %, 20.0 mg, 7.0 %, 1.0 %, 30.0 mg/mL, 0.02 mg/mL, 0.0066 mg/hour, 0.1 mg/mg, 0.01 mg/mg, 2.0 mg/mL, 1.0 mg/mL, 2.0 mg/pump actuation, 0.0116 mg/mg, 0.0754 mg/mg
, Topical, Cream, Cream - Topical, Subarachnoid, Injection, powder, for solution, Injection, powder, for solution - Subarachnoid, Aerosol, spray, Aerosol, spray - Topical, Injection, Injection - Subarachnoid, Ophthalmic, Solution, Solution - Ophthalmic, Cutaneous, Patch, Patch - Cutaneous, Liquid, Liquid - Ophthalmic, Dental; Topical, Gel, Gel - Dental; Topical, Dental, Gel - Dental, Spray, Spray - Topical, Gel - Topical, Buccal, Gel - Buccal, Intraspinal, Powder, for solution, Powder, for solution - Intraspinal, Oral; Topical, Gel - Oral; Topical, Aerosol, metered, Aerosol, metered - Oral; Topical, Solution / drops, Solution / drops - Ophthalmic, Aerosol, metered - Topical, Aerosol, metered - Dental, Oral, Aerosol, Aerosol - Oral, Liquid - Topical, Solution - Topical, Ointment, Ointment - Topical, Aerosol - Topical, Nasal, Spray - Nasal, Patch - Topical, Infiltration; Subcutaneous; Topical, Liquid - Infiltration; Subcutaneous; Topical, Infiltration; Subcutaneous, Liquid - Infiltration; Subcutaneous, Infiltration, Liquid - Infiltration, Infiltration; Topical, Kit, Kit - Infiltration; Topical, Parenteral; Topical, Liquid - Parenteral; Topical, Injection - Oral, Lotion - Topical, Lotion
Dermabrasion
0.07 mg/mg, , 10.0 mg/mL, 0.04 mg/mg, 5.0 mg/mL, 70.0 mg, 0.02 mg/mg, 20.0 mg/mL, 25.0 mg/mL, 2.4 mg/mL, 2.0 %, 0.5 %, 20.0 mg, 7.0 %, 1.0 %, 30.0 mg/mL, 0.02 mg/mL, 0.0066 mg/hour, 0.1 mg/mg, 0.01 mg/mg, 2.0 mg/mL, 1.0 mg/mL, 2.0 mg/pump actuation, 0.0116 mg/mg, 0.0754 mg/mg
, Topical, Cream, Cream - Topical, Subarachnoid, Injection, powder, for solution, Injection, powder, for solution - Subarachnoid, Aerosol, spray, Aerosol, spray - Topical, Injection, Injection - Subarachnoid, Ophthalmic, Solution, Solution - Ophthalmic, Cutaneous, Patch, Patch - Cutaneous, Liquid, Liquid - Ophthalmic, Dental; Topical, Gel, Gel - Dental; Topical, Dental, Gel - Dental, Spray, Spray - Topical, Gel - Topical, Buccal, Gel - Buccal, Intraspinal, Powder, for solution, Powder, for solution - Intraspinal, Oral; Topical, Gel - Oral; Topical, Aerosol, metered, Aerosol, metered - Oral; Topical, Solution / drops, Solution / drops - Ophthalmic, Aerosol, metered - Topical, Aerosol, metered - Dental, Oral, Aerosol, Aerosol - Oral, Liquid - Topical, Solution - Topical, Ointment, Ointment - Topical, Aerosol - Topical, Nasal, Spray - Nasal, Patch - Topical, Infiltration; Subcutaneous; Topical, Liquid - Infiltration; Subcutaneous; Topical, Infiltration; Subcutaneous, Liquid - Infiltration; Subcutaneous, Infiltration, Liquid - Infiltration, Infiltration; Topical, Kit, Kit - Infiltration; Topical, Parenteral; Topical, Liquid - Parenteral; Topical, Injection - Oral, Lotion - Topical, Lotion
minor burns
0.07 mg/mg, , 10.0 mg/mL, 0.04 mg/mg, 5.0 mg/mL, 70.0 mg, 0.02 mg/mg, 20.0 mg/mL, 25.0 mg/mL, 2.4 mg/mL, 2.0 %, 0.5 %, 20.0 mg, 7.0 %, 1.0 %, 30.0 mg/mL, 0.02 mg/mL, 0.0066 mg/hour, 0.1 mg/mg, 0.01 mg/mg, 2.0 mg/mL, 1.0 mg/mL, 2.0 mg/pump actuation, 0.0116 mg/mg, 0.0754 mg/mg
, Topical, Cream, Cream - Topical, Subarachnoid, Injection, powder, for solution, Injection, powder, for solution - Subarachnoid, Aerosol, spray, Aerosol, spray - Topical, Injection, Injection - Subarachnoid, Ophthalmic, Solution, Solution - Ophthalmic, Cutaneous, Patch, Patch - Cutaneous, Liquid, Liquid - Ophthalmic, Dental; Topical, Gel, Gel - Dental; Topical, Dental, Gel - Dental, Spray, Spray - Topical, Gel - Topical, Buccal, Gel - Buccal, Intraspinal, Powder, for solution, Powder, for solution - Intraspinal, Oral; Topical, Gel - Oral; Topical, Aerosol, metered, Aerosol, metered - Oral; Topical, Solution / drops, Solution / drops - Ophthalmic, Aerosol, metered - Topical, Aerosol, metered - Dental, Oral, Aerosol, Aerosol - Oral, Liquid - Topical, Solution - Topical, Ointment, Ointment - Topical, Aerosol - Topical, Nasal, Spray - Nasal, Patch - Topical, Infiltration; Subcutaneous; Topical, Liquid - Infiltration; Subcutaneous; Topical, Infiltration; Subcutaneous, Liquid - Infiltration; Subcutaneous, Infiltration, Liquid - Infiltration, Infiltration; Topical, Kit, Kit - Infiltration; Topical, Parenteral; Topical, Liquid - Parenteral; Topical, Injection - Oral, Lotion - Topical, Lotion
Exanthema
0.07 mg/mg, , 10.0 mg/mL, 0.04 mg/mg, 5.0 mg/mL, 70.0 mg, 0.02 mg/mg, 20.0 mg/mL, 25.0 mg/mL, 2.4 mg/mL, 2.0 %, 0.5 %, 20.0 mg, 7.0 %, 1.0 %, 30.0 mg/mL, 0.02 mg/mL, 0.0066 mg/hour, 0.1 mg/mg, 0.01 mg/mg, 2.0 mg/mL, 1.0 mg/mL, 2.0 mg/pump actuation, 0.0116 mg/mg, 0.0754 mg/mg
, Topical, Cream, Cream - Topical, Subarachnoid, Injection, powder, for solution, Injection, powder, for solution - Subarachnoid, Aerosol, spray, Aerosol, spray - Topical, Injection, Injection - Subarachnoid, Ophthalmic, Solution, Solution - Ophthalmic, Cutaneous, Patch, Patch - Cutaneous, Liquid, Liquid - Ophthalmic, Dental; Topical, Gel, Gel - Dental; Topical, Dental, Gel - Dental, Spray, Spray - Topical, Gel - Topical, Buccal, Gel - Buccal, Intraspinal, Powder, for solution, Powder, for solution - Intraspinal, Oral; Topical, Gel - Oral; Topical, Aerosol, metered, Aerosol, metered - Oral; Topical, Solution / drops, Solution / drops - Ophthalmic, Aerosol, metered - Topical, Aerosol, metered - Dental, Oral, Aerosol, Aerosol - Oral, Liquid - Topical, Solution - Topical, Ointment, Ointment - Topical, Aerosol - Topical, Nasal, Spray - Nasal, Patch - Topical, Infiltration; Subcutaneous; Topical, Liquid - Infiltration; Subcutaneous; Topical, Infiltration; Subcutaneous, Liquid - Infiltration; Subcutaneous, Infiltration, Liquid - Infiltration, Infiltration; Topical, Kit, Kit - Infiltration; Topical, Parenteral; Topical, Liquid - Parenteral; Topical, Injection - Oral, Lotion - Topical, Lotion
Insect Bites and Stings
0.07 mg/mg, , 10.0 mg/mL, 0.04 mg/mg, 5.0 mg/mL, 70.0 mg, 0.02 mg/mg, 20.0 mg/mL, 25.0 mg/mL, 2.4 mg/mL, 2.0 %, 0.5 %, 20.0 mg, 7.0 %, 1.0 %, 30.0 mg/mL, 0.02 mg/mL, 0.0066 mg/hour, 0.1 mg/mg, 0.01 mg/mg, 2.0 mg/mL, 1.0 mg/mL, 2.0 mg/pump actuation, 0.0116 mg/mg, 0.0754 mg/mg
, Topical, Cream, Cream - Topical, Subarachnoid, Injection, powder, for solution, Injection, powder, for solution - Subarachnoid, Aerosol, spray, Aerosol, spray - Topical, Injection, Injection - Subarachnoid, Ophthalmic, Solution, Solution - Ophthalmic, Cutaneous, Patch, Patch - Cutaneous, Liquid, Liquid - Ophthalmic, Dental; Topical, Gel, Gel - Dental; Topical, Dental, Gel - Dental, Spray, Spray - Topical, Gel - Topical, Buccal, Gel - Buccal, Intraspinal, Powder, for solution, Powder, for solution - Intraspinal, Oral; Topical, Gel - Oral; Topical, Aerosol, metered, Aerosol, metered - Oral; Topical, Solution / drops, Solution / drops - Ophthalmic, Aerosol, metered - Topical, Aerosol, metered - Dental, Oral, Aerosol, Aerosol - Oral, Liquid - Topical, Solution - Topical, Ointment, Ointment - Topical, Aerosol - Topical, Nasal, Spray - Nasal, Patch - Topical, Infiltration; Subcutaneous; Topical, Liquid - Infiltration; Subcutaneous; Topical, Infiltration; Subcutaneous, Liquid - Infiltration; Subcutaneous, Infiltration, Liquid - Infiltration, Infiltration; Topical, Kit, Kit - Infiltration; Topical, Parenteral; Topical, Liquid - Parenteral; Topical, Injection - Oral, Lotion - Topical, Lotion
Anesthesia procedures
0.07 mg/mg, , 10.0 mg/mL, 0.04 mg/mg, 5.0 mg/mL, 70.0 mg, 0.02 mg/mg, 20.0 mg/mL, 25.0 mg/mL, 2.4 mg/mL, 2.0 %, 0.5 %, 20.0 mg, 7.0 %, 1.0 %, 30.0 mg/mL, 0.02 mg/mL, 0.0066 mg/hour, 0.1 mg/mg, 0.01 mg/mg, 2.0 mg/mL, 1.0 mg/mL, 2.0 mg/pump actuation, 0.0116 mg/mg, 0.0754 mg/mg
, Topical, Cream, Cream - Topical, Subarachnoid, Injection, powder, for solution, Injection, powder, for solution - Subarachnoid, Aerosol, spray, Aerosol, spray - Topical, Injection, Injection - Subarachnoid, Ophthalmic, Solution, Solution - Ophthalmic, Cutaneous, Patch, Patch - Cutaneous, Liquid, Liquid - Ophthalmic, Dental; Topical, Gel, Gel - Dental; Topical, Dental, Gel - Dental, Spray, Spray - Topical, Gel - Topical, Buccal, Gel - Buccal, Intraspinal, Powder, for solution, Powder, for solution - Intraspinal, Oral; Topical, Gel - Oral; Topical, Aerosol, metered, Aerosol, metered - Oral; Topical, Solution / drops, Solution / drops - Ophthalmic, Aerosol, metered - Topical, Aerosol, metered - Dental, Oral, Aerosol, Aerosol - Oral, Liquid - Topical, Solution - Topical, Ointment, Ointment - Topical, Aerosol - Topical, Nasal, Spray - Nasal, Patch - Topical, Infiltration; Subcutaneous; Topical, Liquid - Infiltration; Subcutaneous; Topical, Infiltration; Subcutaneous, Liquid - Infiltration; Subcutaneous, Infiltration, Liquid - Infiltration, Infiltration; Topical, Kit, Kit - Infiltration; Topical, Parenteral; Topical, Liquid - Parenteral; Topical, Injection - Oral, Lotion - Topical, Lotion
Local Anaesthesia therapy
0.07 mg/mg, , 10.0 mg/mL, 0.04 mg/mg, 5.0 mg/mL, 70.0 mg, 0.02 mg/mg, 20.0 mg/mL, 25.0 mg/mL, 2.4 mg/mL, 2.0 %, 0.5 %, 20.0 mg, 7.0 %, 1.0 %, 30.0 mg/mL, 0.02 mg/mL, 0.0066 mg/hour, 0.1 mg/mg, 0.01 mg/mg, 2.0 mg/mL, 1.0 mg/mL, 2.0 mg/pump actuation, 0.0116 mg/mg, 0.0754 mg/mg
, Topical, Cream, Cream - Topical, Subarachnoid, Injection, powder, for solution, Injection, powder, for solution - Subarachnoid, Aerosol, spray, Aerosol, spray - Topical, Injection, Injection - Subarachnoid, Ophthalmic, Solution, Solution - Ophthalmic, Cutaneous, Patch, Patch - Cutaneous, Liquid, Liquid - Ophthalmic, Dental; Topical, Gel, Gel - Dental; Topical, Dental, Gel - Dental, Spray, Spray - Topical, Gel - Topical, Buccal, Gel - Buccal, Intraspinal, Powder, for solution, Powder, for solution - Intraspinal, Oral; Topical, Gel - Oral; Topical, Aerosol, metered, Aerosol, metered - Oral; Topical, Solution / drops, Solution / drops - Ophthalmic, Aerosol, metered - Topical, Aerosol, metered - Dental, Oral, Aerosol, Aerosol - Oral, Liquid - Topical, Solution - Topical, Ointment, Ointment - Topical, Aerosol - Topical, Nasal, Spray - Nasal, Patch - Topical, Infiltration; Subcutaneous; Topical, Liquid - Infiltration; Subcutaneous; Topical, Infiltration; Subcutaneous, Liquid - Infiltration; Subcutaneous, Infiltration, Liquid - Infiltration, Infiltration; Topical, Kit, Kit - Infiltration; Topical, Parenteral; Topical, Liquid - Parenteral; Topical, Injection - Oral, Lotion - Topical, Lotion
Warnings
There are 20 known major drug interactions with Tetracaine Hydrochloride.Common Tetracaine Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Tetracaine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Tetracaine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Tetracaine is combined with Oliceridine.
Technetium Tc-99m tilmanocept
Major
Tetracaine may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent.
Thalidomide
Major
Tetracaine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Tetracaine Hydrochloride Toxicity & Overdose RiskCommon side effects of the combination cream include redness (47%), skin discoloration (16%), and swelling (14%). Other less common, but more severe side effects may include vomiting, headache, dizziness, fever, and changes in brain activity. It is unknown at what level of concentration overdose occurs with tetracaine, but it is expected to be much lower than with lidocaine, which is 1000 ng/mL.
Tetracaine Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Tetracaine Hydrochloride?
6 active investigations are assessing the potential of Tetracaine Hydrochloride for Dermabrasion, Sunburn alleviation and Local anesthesia.Condition
Clinical Trials
Trial Phases
Sunburn
2 Actively Recruiting
Not Applicable, Phase 2
minor burns
0 Actively Recruiting
Haemorrhoids
1 Actively Recruiting
Not Applicable
Dermabrasion
1 Actively Recruiting
Phase 2
Local Anaesthesia therapy
0 Actively Recruiting
Anesthesia procedures
0 Actively Recruiting
Exanthema
0 Actively Recruiting
Insect Bites and Stings
0 Actively Recruiting
Patient Q&A Section about tetracaine hydrochloride
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Can you buy tetracaine over the counter?
"You cannot buy eye numbing drops over the counter. A medical professional must apply them to avoid serious side effects or chemical dependency."
Answered by AI
How often can you use tetracaine eye drops?
"Patients should use 1-2 drops of the medication every 30 minutes for pain control over a 48-hour period. They will then follow up with the ophthalmologist. Patients with the primary diagnosis of corneal abrasion will be treated with normal saline eye drops."
Answered by AI
What is tetracaine hydrochloride used for?
"Tetracaine eye drops are used to numb the eye before surgery, certain tests, or procedures. The eye drops are used to prevent pain during the procedure. Tetracaine belongs to the group of medicines called local anesthetics. Local anesthetics work by blocking the pain signals at the nerve endings."
Answered by AI
How long do tetracaine eye drops last?
"Although tetracaine is an effective anesthetic, it is not recommended for use on the eyes because it can prevent proper healing of the cornea."
Answered by AI
Clinical Trials for Tetracaine Hydrochloride
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