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What is Optiray 350
IoversolThe Generic name of this drug
Treatment SummaryIoversol is a medicine that contains iodine and other substances to help it dissolve in water. It is used as a contrast dye during medical imaging tests to help the doctor see inside the body more clearly.
Optiray 160is the brand name
Optiray 350 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Optiray 160
Ioversol
2007
5
Effectiveness
How Optiray 350 Affects PatientsIoversol increases contrast in images. When it is injected, iodine levels in the blood reach their highest point and then gradually decrease over time. Depending on what part of the body is being imaged, the time it takes for the contrast to reach its peak can vary from when the iodine levels peak to one hour after the injection. For angiographies, the contrast reaches its peak within 15-120 seconds. In people with healthy kidneys, the contrast will peak within 1-3 minutes and have optimum results in 5-15 minutes.
How Optiray 350 works in the bodyIoversol is a type of dye used to make the inside of the body visible on imaging tests. When injected into the bloodstream, it travels to the places in the body where it is needed for imaging and stays there until it is diluted by the body's fluids. In brains with an intact blood-brain barrier, ioversol does not diffuse to other areas of the brain. However, if the blood-brain barrier is compromised, ioversol can move into the spaces between cells and accumulate there. It also helps create more detailed images on CT scans.
When to interrupt dosage
The advisable dosage of Optiray 350 is contingent upon the indicated condition, for instance venography, ventriculography and intravenous excretory urography. The measure of dosage shifts as per the method of delivery featured in the table below.Condition
Dosage
Administration
left ventriculography
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
angiogram
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
Arteriography
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
coronary arteriography
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
peripheral arteriography
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
Renal Arteriography
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
intravenous excretory urography
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
computerized tomography
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
venography
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
aortography
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
Arteriography
68.0 %, , 74.0 %, 51.0 %, 64.0 %, 34.0 %, 509.0 mg/mL, 636.0 mg/mL, 741.0 mg/mL, 678.0 mg/mL, 339.0 mg/mL, 240.0 mg/mL
, Intravascular, Solution, Solution - Intravascular, Intravascular; Subarachnoid, Solution - Intravascular; Subarachnoid, Intravenous, Solution - Intravenous, Intra-arterial; Intravenous, Injection, Injection - Intra-arterial; Intravenous, Liquid - Intravascular, Liquid, Injection - Intravascular
Warnings
Optiray 350 has one recognized contraindication, and it should not be used if any of the conditions listed in the table below are present.Optiray 350 ContraindicationsCondition
Risk Level
Notes
Hyperthyroidism
Do Not Combine
Common Optiray 350 Drug Interactions
Drug Name
Risk Level
Description
Acrivastine
Minor
Ioversol may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Ioversol may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Almasilate
Minor
Ioversol may decrease the excretion rate of Almasilate which could result in a higher serum level.
Antihemophilic factor (recombinant), PEGylated
Minor
Ioversol may decrease the excretion rate of Antihemophilic factor (recombinant), PEGylated which could result in a higher serum level.
Antithrombin III human
Minor
Ioversol may decrease the excretion rate of Antithrombin III human which could result in a higher serum level.
Optiray 350 Toxicity & Overdose RiskTaking too much ioversol can lead to life-threatening problems in the lungs and heart. Treatment for an overdose should focus on supporting vital functions and providing symptom relief. Animal studies suggest that ioversol is not carcinogenic, mutagenic, or damaging to fertility. If a large dose is given, extra caution must be taken in patients with kidney or liver problems, thyroid issues, or anuria. Serious reactions, including death, have been reported when ioversol was accidentally given into the spine.
Optiray 350 Novel Uses: Which Conditions Have a Clinical Trial Featuring Optiray 350?
An active trial is currently investigating the potential of Optiray 350 to facilitate venography, arteriography and computerized tomographic imaging.Condition
Clinical Trials
Trial Phases
venography
0 Actively Recruiting
peripheral arteriography
0 Actively Recruiting
angiogram
0 Actively Recruiting
aortography
0 Actively Recruiting
left ventriculography
0 Actively Recruiting
Arteriography
0 Actively Recruiting
Arteriography
0 Actively Recruiting
computerized tomography
1 Actively Recruiting
Not Applicable
intravenous excretory urography
0 Actively Recruiting
coronary arteriography
0 Actively Recruiting
Renal Arteriography
0 Actively Recruiting
Optiray 350 Reviews: What are patients saying about Optiray 350?
1Patient Review
3/29/2014 This didn't work at all for me.
Patient Q&A Section about optiray 350
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is there a shortage of optiray contrast?
"at 9:30pm
There is a global shortage of iodinated contrast agents used for CT exams for general radiology and cardiac diagnostics."
Answered by AI
Does optiray have iodine?
"The Optiray 240 solution contains 24% organically bound iodine and has a pH that has been adjusted to fall between 6.0 and 7.4. The solution has been sterilized by autoclaving and does not contain any preservatives."
Answered by AI
What is optiray used for?
"Optiray Injection is a medication used for assisting in diagnostic imaging procedures such as CT scans, X-rays, and MRIs. It can be used alone or in conjunction with other medications."
Answered by AI
What type of contrast is optiray?
"Optiray 350 is a type of contrast agent that contains iodine, which helps it to be more visible on CT scans and other types of x-ray examinations. Contrast agents are often used to help doctors get a better look at blood vessels, organs, and other tissues that don't contain bone."
Answered by AI